CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever
The extracellular secreted NS1 (sNS1) is a major factor contributing to dengue hemorrhagic fever. Here, Shu et al. report sNS1 exists in multiple oligomeric states and presents a tetrameric structure.
Main Authors: | Bo Shu, Justin S. G. Ooi, Aaron W. K. Tan, Thiam-Seng Ng, Wanwisa Dejnirattisai, Juthathip Mongkolsapaya, Guntur Fibriansah, Jian Shi, Victor A. Kostyuchenko, Gavin R. Screaton, Shee-Mei Lok |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-11-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-34415-1 |
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