Mesothelin Expression Is Not Associated with the Presence of Cancer Stem Cell Markers SOX2 and ALDH1 in Ovarian Cancer

Mesothelin Expression Is Not Associated with the Presence of Cancer Stem Cell Markers SOX2 and ALDH1 in Ovarian Cancer

Mesothelin (MSLN) overexpression (OE) is a frequent finding in ovarian carcinomas and increases cell survival and tumor aggressiveness. Since cancer stem cells (CSCs) contribute to pathogenesis, chemoresistance and malignant behavior in ovarian cancer (OC), we hypothesized that MSLN expression could...

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Bibliographic Details
Main Authors: Mariana Nunes, Francisca Pacheco, Ricardo Coelho, Dina Leitão, Sara Ricardo, Leonor David
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
high-grade serous carcinoma
mesothelin
SOX2
ALDH1
cancer stem cells
Online Access:https://www.mdpi.com/1422-0067/23/3/1016

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