Bone regeneration in inflammation with aging and cell-based immunomodulatory therapy
Abstract Aging of the global population increases the incidence of osteoporosis and associated fragility fractures, significantly impacting patient quality of life and healthcare costs. The acute inflammatory reaction is essential to initiate healing after injury. However, aging is associated with “...
Main Authors: | Junichi Kushioka, Simon Kwoon-Ho Chow, Masakazu Toya, Masanori Tsubosaka, Huaishuang Shen, Qi Gao, Xueping Li, Ning Zhang, Stuart B. Goodman |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2023-05-01
|
Series: | Inflammation and Regeneration |
Subjects: | |
Online Access: | https://doi.org/10.1186/s41232-023-00279-1 |
Similar Items
-
Glycolytic reprogramming in macrophages and MSCs during inflammation
by: Xueping Li, et al.
Published: (2023-08-01) -
Sex differences in the therapeutic effect of unaltered versus NFκB sensing IL-4 over-expressing mesenchymal stromal cells in a murine model of chronic inflammatory bone loss
by: Huaishuang Shen, et al.
Published: (2022-08-01) -
Sex differences of NF-κB-targeted therapy for mitigating osteoporosis associated with chronic inflammation of bone
by: Masakazu Toya, et al.
Published: (2024-01-01) -
CCL2 promotes osteogenesis by facilitating macrophage migration during acute inflammation
by: Masakazu Toya, et al.
Published: (2023-06-01) -
Effect on Osteogenic Differentiation of Genetically Modified IL4 or PDGF-BB Over-Expressing and IL4-PDGF-BB Co-Over-Expressing Bone Marrow-Derived Mesenchymal Stromal Cells In Vitro
by: Masanori Tsubosaka, et al.
Published: (2021-10-01)