TRIM5alpha Modulates Immunodeficiency Virus Control in Rhesus Monkeys.

TRIM5alpha Modulates Immunodeficiency Virus Control in Rhesus Monkeys.

The cytoplasmic TRIM5alpha proteins of certain mammalian lineages efficiently recognize the incoming capsids of particular retroviruses and potently restrict infection in a species-specific manner. Successful retroviruses have evolved capsids that are less efficiently recognized by the TRIM5alpha pr...

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Bibliographic Details
Main Authors:	So-Yon Lim, Thomas Rogers, Tiffany Chan, James B Whitney, Jonghwa Kim, Joseph Sodroski, Norman L Letvin
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2010-01-01
Series:	PLoS Pathogens
Online Access:	http://europepmc.org/articles/PMC2809762?pdf=render

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