Health-related quality of life among patients with end-stage renal disease undergoing hemodialysis in Ethiopia: a cross-sectional survey
Abstract Background Measurement of health-related quality of life (HRQOL) enables identification of treatment-related side effects of a disease. Such aspects may negatively impact on patients’ lives and should be taken into consideration in medical decision-making. In sub-Saharan Africa, research fr...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-04-01
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| Series: | Health and Quality of Life Outcomes |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12955-023-02117-x |
| _version_ | 1797840778596188160 |
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| author | Mignote Hailu Gebrie Hussen Mekonnen Asfaw Workagegnehu Hailu Bilchut Helena Lindgren Lena Wettergren |
| author_facet | Mignote Hailu Gebrie Hussen Mekonnen Asfaw Workagegnehu Hailu Bilchut Helena Lindgren Lena Wettergren |
| author_sort | Mignote Hailu Gebrie |
| collection | DOAJ |
| description | Abstract Background Measurement of health-related quality of life (HRQOL) enables identification of treatment-related side effects of a disease. Such aspects may negatively impact on patients’ lives and should be taken into consideration in medical decision-making. In sub-Saharan Africa, research from the perspective of patients with chronic kidney disease is scarce, and it is almost non-existent in patients undergoing hemodialysis. We aimed to determine HRQOL among end-stage renal disease patients undergoing maintenance hemodialysis in Ethiopia and to identify factors associated with HRQOL. Methods A multi-center cross-sectional study was conducted in Addis Ababa, Ethiopia directed to all patients receiving hemodialysis due to kidney failure at 11 randomly-selected government and private hospitals/dialysis centers in the capital of Ethiopia. Data were collected by trained nurses using the KDQOL-36 instrument with five subscales measuring generic and disease-specific HRQOL. Study-specific items were used to collect socio-demographic and clinical data. Factors associated with HRQOL were examined using multivariable linear regression models. Results Four hundred eighty-one patients completed the survey through face-to-face interviews (response rate 96%; mean age 45.34 ± 14.67). The mean scores of the subscales ranged from 25.6 to 66.68 (range 0–100), with higher scores reflecting better health. Factors associated with low HRQOL included older age, female sex, no formal education, poor medication adherence, > 2 hemodialysis sessions/week, lower body mass index (< 18.5), longer duration of hemodialysis treatment (≥ 12 months), and poor social support. Conclusion Patients with kidney failure undergoing hemodialysis in Addis Ababa, Ethiopia, had low HRQOL across all subscales compared to previous studies. Therefore, the implementation of guidelines is crucial to improve patients’ adherence to their prescribed medications. Furthermore, establishing patient support groups and encouraging patients to use the available support resources from family members, neighbors, and friends have the potential to improve patients’ HRQOL. |
| first_indexed | 2024-04-09T16:20:13Z |
| format | Article |
| id | doaj.art-4932a694ac0c4537bfb048391a3d3f96 |
| institution | Directory Open Access Journal |
| issn | 1477-7525 |
| language | English |
| last_indexed | 2024-04-09T16:20:13Z |
| publishDate | 2023-04-01 |
| publisher | BMC |
| record_format | Article |
| series | Health and Quality of Life Outcomes |
| spelling | doaj.art-4932a694ac0c4537bfb048391a3d3f962023-04-23T11:29:02ZengBMCHealth and Quality of Life Outcomes1477-75252023-04-0121111110.1186/s12955-023-02117-xHealth-related quality of life among patients with end-stage renal disease undergoing hemodialysis in Ethiopia: a cross-sectional surveyMignote Hailu Gebrie0Hussen Mekonnen Asfaw1Workagegnehu Hailu Bilchut2Helena Lindgren3Lena Wettergren4College of Medicine and Health Sciences, School of Nursing, University of GondarCollege of Health Sciences, School of Nursing & Midwifery, Department of Nursing, Addis Ababa UniversityCollege of Medicine and Health Sciences, School of Medicine, Department of Internal Medicine, University of GondarDepartment of Women’s and Children’s Health, Division of Reproductive Health, Karolinska InstitutetDepartment of Women’s and Children’s Health, Division of Reproductive Health, Karolinska InstitutetAbstract Background Measurement of health-related quality of life (HRQOL) enables identification of treatment-related side effects of a disease. Such aspects may negatively impact on patients’ lives and should be taken into consideration in medical decision-making. In sub-Saharan Africa, research from the perspective of patients with chronic kidney disease is scarce, and it is almost non-existent in patients undergoing hemodialysis. We aimed to determine HRQOL among end-stage renal disease patients undergoing maintenance hemodialysis in Ethiopia and to identify factors associated with HRQOL. Methods A multi-center cross-sectional study was conducted in Addis Ababa, Ethiopia directed to all patients receiving hemodialysis due to kidney failure at 11 randomly-selected government and private hospitals/dialysis centers in the capital of Ethiopia. Data were collected by trained nurses using the KDQOL-36 instrument with five subscales measuring generic and disease-specific HRQOL. Study-specific items were used to collect socio-demographic and clinical data. Factors associated with HRQOL were examined using multivariable linear regression models. Results Four hundred eighty-one patients completed the survey through face-to-face interviews (response rate 96%; mean age 45.34 ± 14.67). The mean scores of the subscales ranged from 25.6 to 66.68 (range 0–100), with higher scores reflecting better health. Factors associated with low HRQOL included older age, female sex, no formal education, poor medication adherence, > 2 hemodialysis sessions/week, lower body mass index (< 18.5), longer duration of hemodialysis treatment (≥ 12 months), and poor social support. Conclusion Patients with kidney failure undergoing hemodialysis in Addis Ababa, Ethiopia, had low HRQOL across all subscales compared to previous studies. Therefore, the implementation of guidelines is crucial to improve patients’ adherence to their prescribed medications. Furthermore, establishing patient support groups and encouraging patients to use the available support resources from family members, neighbors, and friends have the potential to improve patients’ HRQOL.https://doi.org/10.1186/s12955-023-02117-xEnd-stage renal diseaseHemodialysisHealth-related quality of lifeKDQOL-36Kidney failureAddis Ababa |
| spellingShingle | Mignote Hailu Gebrie Hussen Mekonnen Asfaw Workagegnehu Hailu Bilchut Helena Lindgren Lena Wettergren Health-related quality of life among patients with end-stage renal disease undergoing hemodialysis in Ethiopia: a cross-sectional survey Health and Quality of Life Outcomes End-stage renal disease Hemodialysis Health-related quality of life KDQOL-36 Kidney failure Addis Ababa |
| title | Health-related quality of life among patients with end-stage renal disease undergoing hemodialysis in Ethiopia: a cross-sectional survey |
| title_full | Health-related quality of life among patients with end-stage renal disease undergoing hemodialysis in Ethiopia: a cross-sectional survey |
| title_fullStr | Health-related quality of life among patients with end-stage renal disease undergoing hemodialysis in Ethiopia: a cross-sectional survey |
| title_full_unstemmed | Health-related quality of life among patients with end-stage renal disease undergoing hemodialysis in Ethiopia: a cross-sectional survey |
| title_short | Health-related quality of life among patients with end-stage renal disease undergoing hemodialysis in Ethiopia: a cross-sectional survey |
| title_sort | health related quality of life among patients with end stage renal disease undergoing hemodialysis in ethiopia a cross sectional survey |
| topic | End-stage renal disease Hemodialysis Health-related quality of life KDQOL-36 Kidney failure Addis Ababa |
| url | https://doi.org/10.1186/s12955-023-02117-x |
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