Low risk for diabetic complications in type 1 diabetes patients carrying a protective insulin gene variant
Type 1 diabetes patients carrying a ‘protective’ insulin gene (INS) variant present a disease endotype with reduced insulin antibody titers, preserved beta cell function and improved glycemic control. We tested whether this protective INS variant associated with lowered risk for development of proli...
Main Authors: | René van Tienhoven, Anh Nguyet Vu, John S. Kaddis, Bart O. Roep |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2023-01-01
|
Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879388/?tool=EBI |
Similar Items
-
Low risk for diabetic complications in type 1 diabetes patients carrying a protective insulin gene variant.
by: René van Tienhoven, et al.
Published: (2023-01-01) -
Induction of islet autoimmunity to defective ribosomal product of the insulin gene as neoantigen after anti-cancer immunotherapy leading to autoimmune diabetes
by: Rene van Tienhoven, et al.
Published: (2024-03-01) -
Functional Impact of Risk Gene Variants on the Autoimmune Responses in Type 1 Diabetes
by: Chelsea Gootjes, et al.
Published: (2022-05-01) -
The need and benefit of immune monitoring to define patient and disease heterogeneity, mechanisms of therapeutic action and efficacy of intervention therapy for precision medicine in type 1 diabetes
by: Bart O. Roep
Published: (2023-01-01) -
Cutaneous complications of insulin therapy in patients with Type1 diabetes mellitus
by: Munib A. Alzubaidi
Published: (2010-01-01)