Seasonal Changes in Lower Urinary Tract Symptoms in Japanese Men With Benign Prostatic Hyperplasia Treated With α-Blockers
Purpose To investigate whether seasonal changes occurred in lower urinary tract symptoms (LUTS) in patients with benign prostatic hyperplasia (BPH). Methods Patients aged 50 years and older with BPH treated with α1-blockers were enrolled. The International Prostate Symptom Score (IPSS), quality of l...
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| Format: | Article |
| Language: | English |
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Korean Continence Society
2017-09-01
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| Series: | International Neurourology Journal |
| Subjects: | |
| Online Access: | http://www.einj.org/upload/pdf/inj-1734830-415.pdf |
| _version_ | 1819266464115326976 |
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| author | Minoru Kobayashi Akinori Nukui Takao Kamai |
| author_facet | Minoru Kobayashi Akinori Nukui Takao Kamai |
| author_sort | Minoru Kobayashi |
| collection | DOAJ |
| description | Purpose To investigate whether seasonal changes occurred in lower urinary tract symptoms (LUTS) in patients with benign prostatic hyperplasia (BPH). Methods Patients aged 50 years and older with BPH treated with α1-blockers were enrolled. The International Prostate Symptom Score (IPSS), quality of life (QoL) score, maximum and average flow rate, voided volume, and postvoid residual volume were measured in summer and winter. Results A total of 164 patients were enrolled. The total IPSS and QoL index did not show a significant difference between the 2 seasons. When the IPSS was divided into storage symptoms and voiding symptoms, storage symptoms in winter were substantially but nonsignificantly higher than those in summer (P=0.056). Of the 7 individual symptoms in the IPSS, a significant seasonal difference was observed only for nocturia, with a higher score in winter. Moreover, none of the uroflowmetric parameters showed a seasonal change. Voided volume had significant correlations with each symptom (urgency and nocturia) and overall subjective scores (storage, total IPSS, and QoL) exclusively in summer, while this correlation remained only for nocturia in winter. Conclusions As it has generally been assumed that LUTS deteriorate in winter, the present study corroborated that the severity of storage symptoms was higher in winter than in summer, even in patients treated with α1-blockers. In contrast, a seasonal difference was not observed in the uroflowmetric parameters, which may be partly due to the loss of the correlation between subjective and objective measurements of storage symptoms in winter. |
| first_indexed | 2024-12-23T21:01:41Z |
| format | Article |
| id | doaj.art-49383a0ccdc040e980a16d90f9bae236 |
| institution | Directory Open Access Journal |
| issn | 2093-4777 2093-6931 |
| language | English |
| last_indexed | 2024-12-23T21:01:41Z |
| publishDate | 2017-09-01 |
| publisher | Korean Continence Society |
| record_format | Article |
| series | International Neurourology Journal |
| spelling | doaj.art-49383a0ccdc040e980a16d90f9bae2362022-12-21T17:31:21ZengKorean Continence SocietyInternational Neurourology Journal2093-47772093-69312017-09-0121319720310.5213/inj.1734830.415682Seasonal Changes in Lower Urinary Tract Symptoms in Japanese Men With Benign Prostatic Hyperplasia Treated With α-BlockersMinoru Kobayashi0Akinori Nukui1Takao Kamai2 Department of Urology, Utsunomiya Memorial Hospital, Tochigi, Japan Department of Urology, Nasu Red Cross Hospital, Tochigi, Japan Department of Urology, Dokkyo Medical University, Tochigi, JapanPurpose To investigate whether seasonal changes occurred in lower urinary tract symptoms (LUTS) in patients with benign prostatic hyperplasia (BPH). Methods Patients aged 50 years and older with BPH treated with α1-blockers were enrolled. The International Prostate Symptom Score (IPSS), quality of life (QoL) score, maximum and average flow rate, voided volume, and postvoid residual volume were measured in summer and winter. Results A total of 164 patients were enrolled. The total IPSS and QoL index did not show a significant difference between the 2 seasons. When the IPSS was divided into storage symptoms and voiding symptoms, storage symptoms in winter were substantially but nonsignificantly higher than those in summer (P=0.056). Of the 7 individual symptoms in the IPSS, a significant seasonal difference was observed only for nocturia, with a higher score in winter. Moreover, none of the uroflowmetric parameters showed a seasonal change. Voided volume had significant correlations with each symptom (urgency and nocturia) and overall subjective scores (storage, total IPSS, and QoL) exclusively in summer, while this correlation remained only for nocturia in winter. Conclusions As it has generally been assumed that LUTS deteriorate in winter, the present study corroborated that the severity of storage symptoms was higher in winter than in summer, even in patients treated with α1-blockers. In contrast, a seasonal difference was not observed in the uroflowmetric parameters, which may be partly due to the loss of the correlation between subjective and objective measurements of storage symptoms in winter.http://www.einj.org/upload/pdf/inj-1734830-415.pdfAdrenergic alpha-AntagonistsProstatic HyperplasiaLower Urinary Tract SymptomsSeasonal ChangeUrodynamics |
| spellingShingle | Minoru Kobayashi Akinori Nukui Takao Kamai Seasonal Changes in Lower Urinary Tract Symptoms in Japanese Men With Benign Prostatic Hyperplasia Treated With α-Blockers International Neurourology Journal Adrenergic alpha-Antagonists Prostatic Hyperplasia Lower Urinary Tract Symptoms Seasonal Change Urodynamics |
| title | Seasonal Changes in Lower Urinary Tract Symptoms in Japanese Men With Benign Prostatic Hyperplasia Treated With α-Blockers |
| title_full | Seasonal Changes in Lower Urinary Tract Symptoms in Japanese Men With Benign Prostatic Hyperplasia Treated With α-Blockers |
| title_fullStr | Seasonal Changes in Lower Urinary Tract Symptoms in Japanese Men With Benign Prostatic Hyperplasia Treated With α-Blockers |
| title_full_unstemmed | Seasonal Changes in Lower Urinary Tract Symptoms in Japanese Men With Benign Prostatic Hyperplasia Treated With α-Blockers |
| title_short | Seasonal Changes in Lower Urinary Tract Symptoms in Japanese Men With Benign Prostatic Hyperplasia Treated With α-Blockers |
| title_sort | seasonal changes in lower urinary tract symptoms in japanese men with benign prostatic hyperplasia treated with α blockers |
| topic | Adrenergic alpha-Antagonists Prostatic Hyperplasia Lower Urinary Tract Symptoms Seasonal Change Urodynamics |
| url | http://www.einj.org/upload/pdf/inj-1734830-415.pdf |
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