A new scoring system to stratify risk in unstable angina
<p>Abstract</p> <p>Background</p> <p>We performed this study to develop a new scoring system to stratify different levels of risk in patients admitted to hospital with a diagnosis of unstable angina (UA), which is a complex syndrome that encompasses different outcomes....
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2003-08-01
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| Series: | BMC Cardiovascular Disorders |
| Online Access: | http://www.biomedcentral.com/1471-2261/3/8 |
| _version_ | 1811283554921873408 |
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| author | Salzberg Simón Fuselli Juan Guetta Javier Gagliardi Juan A Piombo Alfredo C Fairman Enrique Bertolasi Carlos |
| author_facet | Salzberg Simón Fuselli Juan Guetta Javier Gagliardi Juan A Piombo Alfredo C Fairman Enrique Bertolasi Carlos |
| author_sort | Salzberg Simón |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>We performed this study to develop a new scoring system to stratify different levels of risk in patients admitted to hospital with a diagnosis of unstable angina (UA), which is a complex syndrome that encompasses different outcomes. Many prognostic variables have been described but few efforts have been made to group them in order to enhance their individual predictive power.</p> <p>Methods</p> <p>In a first phase, 473 patients were prospectively analyzed to determine which factors were significantly associated with the in-hospital occurrence of refractory ischemia, acute myocardial infarction (AMI) or death. A risk score ranging from 0 to 10 points was developed using a multivariate analysis. In a second phase, such score was validated in a new sample of 242 patients and it was finally applied to the entire population (n = 715).</p> <p>Results</p> <p>ST-segment deviation on the electrocardiogram, age ≥ 70 years, previous bypass surgery and troponin T ≥ 0.1 ng/mL were found as independent prognostic variables. A clear distinction was shown among categories of low, intermediate and high risk, defined according to the risk score. The incidence of the triple end-point was 6 %, 19.2 % and 44.7 % respectively, and the figures for AMI or death were 2 %, 11.4 % and 27.6 % respectively (p < 0.001).</p> <p>Conclusions</p> <p>This new scoring system is simple and easy to achieve. It allows a very good stratification of risk in patients having a clinical diagnosis of UA. They may be divided in three categories, which could be of help in the decision-making process.</p> |
| first_indexed | 2024-04-13T02:14:47Z |
| format | Article |
| id | doaj.art-493bdee2dab94c21b11bee92376421ce |
| institution | Directory Open Access Journal |
| issn | 1471-2261 |
| language | English |
| last_indexed | 2024-04-13T02:14:47Z |
| publishDate | 2003-08-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cardiovascular Disorders |
| spelling | doaj.art-493bdee2dab94c21b11bee92376421ce2022-12-22T03:07:12ZengBMCBMC Cardiovascular Disorders1471-22612003-08-0131810.1186/1471-2261-3-8A new scoring system to stratify risk in unstable anginaSalzberg SimónFuselli JuanGuetta JavierGagliardi Juan APiombo Alfredo CFairman EnriqueBertolasi Carlos<p>Abstract</p> <p>Background</p> <p>We performed this study to develop a new scoring system to stratify different levels of risk in patients admitted to hospital with a diagnosis of unstable angina (UA), which is a complex syndrome that encompasses different outcomes. Many prognostic variables have been described but few efforts have been made to group them in order to enhance their individual predictive power.</p> <p>Methods</p> <p>In a first phase, 473 patients were prospectively analyzed to determine which factors were significantly associated with the in-hospital occurrence of refractory ischemia, acute myocardial infarction (AMI) or death. A risk score ranging from 0 to 10 points was developed using a multivariate analysis. In a second phase, such score was validated in a new sample of 242 patients and it was finally applied to the entire population (n = 715).</p> <p>Results</p> <p>ST-segment deviation on the electrocardiogram, age ≥ 70 years, previous bypass surgery and troponin T ≥ 0.1 ng/mL were found as independent prognostic variables. A clear distinction was shown among categories of low, intermediate and high risk, defined according to the risk score. The incidence of the triple end-point was 6 %, 19.2 % and 44.7 % respectively, and the figures for AMI or death were 2 %, 11.4 % and 27.6 % respectively (p < 0.001).</p> <p>Conclusions</p> <p>This new scoring system is simple and easy to achieve. It allows a very good stratification of risk in patients having a clinical diagnosis of UA. They may be divided in three categories, which could be of help in the decision-making process.</p>http://www.biomedcentral.com/1471-2261/3/8 |
| spellingShingle | Salzberg Simón Fuselli Juan Guetta Javier Gagliardi Juan A Piombo Alfredo C Fairman Enrique Bertolasi Carlos A new scoring system to stratify risk in unstable angina BMC Cardiovascular Disorders |
| title | A new scoring system to stratify risk in unstable angina |
| title_full | A new scoring system to stratify risk in unstable angina |
| title_fullStr | A new scoring system to stratify risk in unstable angina |
| title_full_unstemmed | A new scoring system to stratify risk in unstable angina |
| title_short | A new scoring system to stratify risk in unstable angina |
| title_sort | new scoring system to stratify risk in unstable angina |
| url | http://www.biomedcentral.com/1471-2261/3/8 |
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