Evaluating the repeatability and set-up sensitivity of a large field of view distortion phantom and software for magnetic resonance-only radiotherapy

Background and purpose: Magnetic Resonance (MR)-only radiotherapy requires geometrically accurate MR images over the full scanner Field of View (FoV). This study aimed to investigate the repeatability of distortion measurements made using a commercial large FoV phantom and analysis software and the...

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Main Authors: Jonathan Wyatt, Stephen Hedley, Emily Johnstone, Richard Speight, Charles Kelly, Ann Henry, Susan Short, Louise Murray, David Sebag-Montefiore, Hazel McCallum
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Physics and Imaging in Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S240563161730060X
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author Jonathan Wyatt
Stephen Hedley
Emily Johnstone
Richard Speight
Charles Kelly
Ann Henry
Susan Short
Louise Murray
David Sebag-Montefiore
Hazel McCallum
author_facet Jonathan Wyatt
Stephen Hedley
Emily Johnstone
Richard Speight
Charles Kelly
Ann Henry
Susan Short
Louise Murray
David Sebag-Montefiore
Hazel McCallum
author_sort Jonathan Wyatt
collection DOAJ
description Background and purpose: Magnetic Resonance (MR)-only radiotherapy requires geometrically accurate MR images over the full scanner Field of View (FoV). This study aimed to investigate the repeatability of distortion measurements made using a commercial large FoV phantom and analysis software and the sensitivity of these measurements to small set-up errors. Materials and methods: Geometric distortion was measured using a commercial phantom and software with 2D and 3D acquisition sequences on three different MR scanners. Two sets of repeatability measurements were made: three scans acquired without moving the phantom between scans (single set-up) and five scans acquired with the phantom re-set up in between each scan (repeated set-up). The set-up sensitivity was assessed by scanning the phantom with an intentional 1 mm lateral offset and independently an intentional 1° rotation. Results: The mean standard deviation of distortion for all phantom markers for the repeated set-up scans was <0.4mm for all scanners and sequences. For the 1mm lateral offset scan 90% of the markers agreed within two standard deviations of the mean of the repeated set-up scan (median of all scanners and sequences, range 78%–93%). For the 1° rotation scan, 80% of markers agreed within two standard deviations of the mean (range 69%–93%). Conclusions: Geometric distortion measurements using a commercial phantom and associated software appear repeatable, although with some sensitivity to set-up errors. This suggests the phantom and software are appropriate for commissioning a MR-only radiotherapy workflow. Keywords: Geometric distortion, Magnetic resonance imaging, Radiotherapy, MR-only radiotherapy planning
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spelling doaj.art-493c3732c7ee4efcb147613ffebea67c2022-12-21T17:30:44ZengElsevierPhysics and Imaging in Radiation Oncology2405-63162018-04-0163138Evaluating the repeatability and set-up sensitivity of a large field of view distortion phantom and software for magnetic resonance-only radiotherapyJonathan Wyatt0Stephen Hedley1Emily Johnstone2Richard Speight3Charles Kelly4Ann Henry5Susan Short6Louise Murray7David Sebag-Montefiore8Hazel McCallum9Northern Centre for Cancer Care, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK; Corresponding author.Northern Centre for Cancer Care, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UKLeeds Institute of Cancer and Pathology, University of Leeds, Leeds, UKLeeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UKNorthern Centre for Cancer Care, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UKLeeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK; Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UKLeeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK; Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UKLeeds Institute of Cancer and Pathology, University of Leeds, Leeds, UKLeeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK; Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UKNorthern Centre for Cancer Care, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UKBackground and purpose: Magnetic Resonance (MR)-only radiotherapy requires geometrically accurate MR images over the full scanner Field of View (FoV). This study aimed to investigate the repeatability of distortion measurements made using a commercial large FoV phantom and analysis software and the sensitivity of these measurements to small set-up errors. Materials and methods: Geometric distortion was measured using a commercial phantom and software with 2D and 3D acquisition sequences on three different MR scanners. Two sets of repeatability measurements were made: three scans acquired without moving the phantom between scans (single set-up) and five scans acquired with the phantom re-set up in between each scan (repeated set-up). The set-up sensitivity was assessed by scanning the phantom with an intentional 1 mm lateral offset and independently an intentional 1° rotation. Results: The mean standard deviation of distortion for all phantom markers for the repeated set-up scans was <0.4mm for all scanners and sequences. For the 1mm lateral offset scan 90% of the markers agreed within two standard deviations of the mean of the repeated set-up scan (median of all scanners and sequences, range 78%–93%). For the 1° rotation scan, 80% of markers agreed within two standard deviations of the mean (range 69%–93%). Conclusions: Geometric distortion measurements using a commercial phantom and associated software appear repeatable, although with some sensitivity to set-up errors. This suggests the phantom and software are appropriate for commissioning a MR-only radiotherapy workflow. Keywords: Geometric distortion, Magnetic resonance imaging, Radiotherapy, MR-only radiotherapy planninghttp://www.sciencedirect.com/science/article/pii/S240563161730060X
spellingShingle Jonathan Wyatt
Stephen Hedley
Emily Johnstone
Richard Speight
Charles Kelly
Ann Henry
Susan Short
Louise Murray
David Sebag-Montefiore
Hazel McCallum
Evaluating the repeatability and set-up sensitivity of a large field of view distortion phantom and software for magnetic resonance-only radiotherapy
Physics and Imaging in Radiation Oncology
title Evaluating the repeatability and set-up sensitivity of a large field of view distortion phantom and software for magnetic resonance-only radiotherapy
title_full Evaluating the repeatability and set-up sensitivity of a large field of view distortion phantom and software for magnetic resonance-only radiotherapy
title_fullStr Evaluating the repeatability and set-up sensitivity of a large field of view distortion phantom and software for magnetic resonance-only radiotherapy
title_full_unstemmed Evaluating the repeatability and set-up sensitivity of a large field of view distortion phantom and software for magnetic resonance-only radiotherapy
title_short Evaluating the repeatability and set-up sensitivity of a large field of view distortion phantom and software for magnetic resonance-only radiotherapy
title_sort evaluating the repeatability and set up sensitivity of a large field of view distortion phantom and software for magnetic resonance only radiotherapy
url http://www.sciencedirect.com/science/article/pii/S240563161730060X
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