SNP arrays evaluation as tools in genetic improvement in Corriedale sheep in Uruguay
One control strategy for gastrointestinal nematodes (GIN) is genetic selection. This study´s objective was to compare eggs per gram of feces (FEC) and fiber diameter (FD) estimated breeding values (EBV) and genomic EBV (GEBV) in Corriedale breed. Analysis included 19547 lambs with data, and 454, 711...
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| Format: | Article |
| Language: | English |
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Universidad de la República, Facultad de Agronomía
2022-08-01
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| Series: | Agrociencia Uruguay |
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| Online Access: | https://doi.org/10.31285/AGRO.26.998 |
| _version_ | 1797725043184107520 |
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| author | Beatriz Carracelas Elly Ana Navajas Brenda Vera Gabriel Ciappesoni |
| author_facet | Beatriz Carracelas Elly Ana Navajas Brenda Vera Gabriel Ciappesoni |
| author_sort | Beatriz Carracelas |
| collection | DOAJ |
| description | One control strategy for gastrointestinal nematodes (GIN) is genetic selection. This study´s objective was to compare eggs per gram of feces (FEC) and fiber diameter (FD) estimated breeding values (EBV) and genomic EBV (GEBV) in Corriedale breed. Analysis included 19547 lambs with data, and 454, 711 and 383 genotypes from 170, 507 and 50K SNP chips, respectively. A univariate animal model was used for EBV and GEBV estimation, which included contemporary group, type of birth and dam age as fixed effects, and age at recording as covariate. Differential weights (α) were considered in the genomic relationship matrix (G), and the best fit models were identified using Akaike´s Information Criterion (AIC), which were later used for GEBV and accuracies estimation. The use of α only impacted on low density SNP chips. No differences were observed in mean accuracies for the whole population. However, in the genotyped subgroup accuracies increased by 2% with the 170 SNP chip (α=0.25), and by 5% (α=0.5) and 14% (α=0.75) with the 507 SNP chip. No differences were observed in FD EBV and GEBV mean accuracies. These results show that it is possible to increase GEBV accuracies despite the use of low-density chips. |
| first_indexed | 2024-03-12T10:25:30Z |
| format | Article |
| id | doaj.art-493dbebb899242528d111c98717208b8 |
| institution | Directory Open Access Journal |
| issn | 2730-5066 |
| language | English |
| last_indexed | 2024-03-12T10:25:30Z |
| publishDate | 2022-08-01 |
| publisher | Universidad de la República, Facultad de Agronomía |
| record_format | Article |
| series | Agrociencia Uruguay |
| spelling | doaj.art-493dbebb899242528d111c98717208b82023-09-02T09:44:54ZengUniversidad de la República, Facultad de AgronomíaAgrociencia Uruguay2730-50662022-08-01262e99810.31285/AGRO.26.998SNP arrays evaluation as tools in genetic improvement in Corriedale sheep in UruguayBeatriz Carracelas0https://orcid.org/0000-0003-1340-367XElly Ana Navajas1https://orcid.org/0000-0002-9018-4741Brenda Vera2https://orcid.org/0000-0002-5706-4721Gabriel Ciappesoni3https://orcid.org/0000-0002-0091-3956Instituto Nacional de Investigación Agropecuaria (INIA), Unidad de Biotecnología, Las Brujas, UruguayInstituto Nacional de Investigación Agropecuaria (INIA), Unidad de Biotecnología, Las Brujas, UruguayInstituto Nacional de Investigación Agropecuaria (INIA), Programa de Producción de Carne y Lana, Las Brujas, UruguayInstituto Nacional de Investigación Agropecuaria (INIA), Programa de Producción de Carne y Lana, Las Brujas, UruguayOne control strategy for gastrointestinal nematodes (GIN) is genetic selection. This study´s objective was to compare eggs per gram of feces (FEC) and fiber diameter (FD) estimated breeding values (EBV) and genomic EBV (GEBV) in Corriedale breed. Analysis included 19547 lambs with data, and 454, 711 and 383 genotypes from 170, 507 and 50K SNP chips, respectively. A univariate animal model was used for EBV and GEBV estimation, which included contemporary group, type of birth and dam age as fixed effects, and age at recording as covariate. Differential weights (α) were considered in the genomic relationship matrix (G), and the best fit models were identified using Akaike´s Information Criterion (AIC), which were later used for GEBV and accuracies estimation. The use of α only impacted on low density SNP chips. No differences were observed in mean accuracies for the whole population. However, in the genotyped subgroup accuracies increased by 2% with the 170 SNP chip (α=0.25), and by 5% (α=0.5) and 14% (α=0.75) with the 507 SNP chip. No differences were observed in FD EBV and GEBV mean accuracies. These results show that it is possible to increase GEBV accuracies despite the use of low-density chips.https://doi.org/10.31285/AGRO.26.998accuracycorriedalefecgebv |
| spellingShingle | Beatriz Carracelas Elly Ana Navajas Brenda Vera Gabriel Ciappesoni SNP arrays evaluation as tools in genetic improvement in Corriedale sheep in Uruguay Agrociencia Uruguay accuracy corriedale fec gebv |
| title | SNP arrays evaluation as tools in genetic improvement in Corriedale sheep in Uruguay |
| title_full | SNP arrays evaluation as tools in genetic improvement in Corriedale sheep in Uruguay |
| title_fullStr | SNP arrays evaluation as tools in genetic improvement in Corriedale sheep in Uruguay |
| title_full_unstemmed | SNP arrays evaluation as tools in genetic improvement in Corriedale sheep in Uruguay |
| title_short | SNP arrays evaluation as tools in genetic improvement in Corriedale sheep in Uruguay |
| title_sort | snp arrays evaluation as tools in genetic improvement in corriedale sheep in uruguay |
| topic | accuracy corriedale fec gebv |
| url | https://doi.org/10.31285/AGRO.26.998 |
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