Churg–Strauss syndrome‐associated heart failure and left ventricular thrombosis
Abstract We present a case of a 47‐year‐old woman with a history of asthma and mononeuritis who presented with shortness of breath and fatigue. Heart failure was diagnosed and echocardiography revealed large floating thrombi attached to the left ventricular walls. Cardiac magnetic resonance imaging...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-06-01
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| Series: | ESC Heart Failure |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ehf2.14244 |
| _version_ | 1797824635480309760 |
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| author | Sotiria Liori Eleftherios Samiotis Dionysia Birba Pelagia Katsimbri Maria Mademli Eleni Bakola Georgios Tsivgoulis Estela Quris Michael Bonios Maria Kalabaliki Dimitrios Farmakis John Parissis Alexandra Frogoudaki |
| author_facet | Sotiria Liori Eleftherios Samiotis Dionysia Birba Pelagia Katsimbri Maria Mademli Eleni Bakola Georgios Tsivgoulis Estela Quris Michael Bonios Maria Kalabaliki Dimitrios Farmakis John Parissis Alexandra Frogoudaki |
| author_sort | Sotiria Liori |
| collection | DOAJ |
| description | Abstract We present a case of a 47‐year‐old woman with a history of asthma and mononeuritis who presented with shortness of breath and fatigue. Heart failure was diagnosed and echocardiography revealed large floating thrombi attached to the left ventricular walls. Cardiac magnetic resonance imaging showed evidence of myocarditis and angiitis. Blood count revealed eosinophilia. She was diagnosed with eosinophilic granulomatosis with polyangiitis or Churg–Strauss syndrome (CSS) according to recently updated criteria. Medical management with specific aetiology (anticoagulation or immunosuppression) and heart failure treatment resulted in clinical improvement. We further discuss the diagnostic approach of CSS with cardiovascular complications and therapeutic management. |
| first_indexed | 2024-03-13T10:41:55Z |
| format | Article |
| id | doaj.art-49425936e93944da93eae58337a7aeb6 |
| institution | Directory Open Access Journal |
| issn | 2055-5822 |
| language | English |
| last_indexed | 2024-03-13T10:41:55Z |
| publishDate | 2023-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | ESC Heart Failure |
| spelling | doaj.art-49425936e93944da93eae58337a7aeb62023-05-18T03:08:57ZengWileyESC Heart Failure2055-58222023-06-011032107211210.1002/ehf2.14244Churg–Strauss syndrome‐associated heart failure and left ventricular thrombosisSotiria Liori0Eleftherios Samiotis1Dionysia Birba2Pelagia Katsimbri3Maria Mademli4Eleni Bakola5Georgios Tsivgoulis6Estela Quris7Michael Bonios8Maria Kalabaliki9Dimitrios Farmakis10John Parissis11Alexandra Frogoudaki12Second Department of Cardiology Attikon University Hospital, School of Medicine, National and Kapodistrian University of Athens Athens GreeceSecond Department of Cardiology Attikon University Hospital, School of Medicine, National and Kapodistrian University of Athens Athens GreeceSecond Department of Cardiology Attikon University Hospital, School of Medicine, National and Kapodistrian University of Athens Athens GreeceRheumatology and Clinical Immunology Unit, Fourth Department of Internal Medicine Attikon University Hospital, School of Medicine, National and Kapodistrian University of Athens Athens GreeceSecond Department of Radiology Attikon University Hospital, School of Medicine, National and Kapodistrian University of Athens Athens GreeceSecond Department of Neurology Attikon University Hospital, School of Medicine, National and Kapodistrian University of Athens Athens GreeceSecond Department of Neurology Attikon University Hospital, School of Medicine, National and Kapodistrian University of Athens Athens GreeceSecond Department of Cardiology Attikon University Hospital, School of Medicine, National and Kapodistrian University of Athens Athens GreeceHeart Failure and Transplant Unit Onassis Cardiac Surgery Center Athens GreeceSecond Department of Cardiology Attikon University Hospital, School of Medicine, National and Kapodistrian University of Athens Athens GreeceUniversity of Cyprus Medical School Nicosia CyprusSecond Department of Cardiology Attikon University Hospital, School of Medicine, National and Kapodistrian University of Athens Athens GreeceSecond Department of Cardiology Attikon University Hospital, School of Medicine, National and Kapodistrian University of Athens Athens GreeceAbstract We present a case of a 47‐year‐old woman with a history of asthma and mononeuritis who presented with shortness of breath and fatigue. Heart failure was diagnosed and echocardiography revealed large floating thrombi attached to the left ventricular walls. Cardiac magnetic resonance imaging showed evidence of myocarditis and angiitis. Blood count revealed eosinophilia. She was diagnosed with eosinophilic granulomatosis with polyangiitis or Churg–Strauss syndrome (CSS) according to recently updated criteria. Medical management with specific aetiology (anticoagulation or immunosuppression) and heart failure treatment resulted in clinical improvement. We further discuss the diagnostic approach of CSS with cardiovascular complications and therapeutic management.https://doi.org/10.1002/ehf2.14244Eosinophilic granulomatosis with polyangiitisChurg–Strauss syndromeHeart failureLeft ventricular thrombusMyocarditis |
| spellingShingle | Sotiria Liori Eleftherios Samiotis Dionysia Birba Pelagia Katsimbri Maria Mademli Eleni Bakola Georgios Tsivgoulis Estela Quris Michael Bonios Maria Kalabaliki Dimitrios Farmakis John Parissis Alexandra Frogoudaki Churg–Strauss syndrome‐associated heart failure and left ventricular thrombosis ESC Heart Failure Eosinophilic granulomatosis with polyangiitis Churg–Strauss syndrome Heart failure Left ventricular thrombus Myocarditis |
| title | Churg–Strauss syndrome‐associated heart failure and left ventricular thrombosis |
| title_full | Churg–Strauss syndrome‐associated heart failure and left ventricular thrombosis |
| title_fullStr | Churg–Strauss syndrome‐associated heart failure and left ventricular thrombosis |
| title_full_unstemmed | Churg–Strauss syndrome‐associated heart failure and left ventricular thrombosis |
| title_short | Churg–Strauss syndrome‐associated heart failure and left ventricular thrombosis |
| title_sort | churg strauss syndrome associated heart failure and left ventricular thrombosis |
| topic | Eosinophilic granulomatosis with polyangiitis Churg–Strauss syndrome Heart failure Left ventricular thrombus Myocarditis |
| url | https://doi.org/10.1002/ehf2.14244 |
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