Metabolic Consequences of Polyphosphate Synthesis and Imminent Phosphate Limitation

Metabolic Consequences of Polyphosphate Synthesis and Imminent Phosphate Limitation

ABSTRACT Cells stabilize intracellular inorganic phosphate (Pi) to compromise between large biosynthetic needs and detrimental bioenergetic effects of Pi. Pi homeostasis in eukaryotes uses Syg1/Pho81/Xpr1 (SPX) domains, which are receptors for inositol pyrophosphates. We explored how polymerization...

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Bibliographic Details
Main Authors: Geun-Don Kim, Danye Qiu, Henning Jacob Jessen, Andreas Mayer
Format: Article
Language:English
Published: American Society for Microbiology 2023-06-01
Series:mBio
Subjects:
Saccharomyces cerevisiae
acidocalcisome
phosphate signalling
polyphosphate
SPX domains
Online Access:https://journals.asm.org/doi/10.1128/mbio.00102-23

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