Asymmetric organocatalytic decarboxylative Mannich reaction using β-keto acids: A new protocol for the synthesis of chiral β-amino ketones
The first decarboxylative Mannich reaction employing β-keto acids, catalyzed by cinchonine-derived bifunctional thiourea catalyst has been described. The desired β-amino ketones were obtained in excellent yields and with moderate to good enantioselectivities.
| मुख्य लेखकों: | , , |
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| स्वरूप: | लेख |
| भाषा: | English |
| प्रकाशित: |
Beilstein-Institut
2012-08-01
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| श्रृंखला: | Beilstein Journal of Organic Chemistry |
| विषय: | |
| ऑनलाइन पहुंच: | https://doi.org/10.3762/bjoc.8.144 |