Hepatitis C virus hypervariable region 1 variants presented on hepatitis B virus capsid-like particles induce cross-neutralizing antibodies.

Hepatitis C virus hypervariable region 1 variants presented on hepatitis B virus capsid-like particles induce cross-neutralizing antibodies.

Hepatitis C virus (HCV) infection is still a serious global health burden. Despite improved therapeutic options, a preventative vaccine would be desirable especially in undeveloped countries. Traditionally, highly conserved epitopes are targets for antibody-based prophylactic vaccines. In HCV-infect...

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Bibliographic Details
Main Authors: Milena Lange, Melanie Fiedler, Dorothea Bankwitz, William Osburn, Sergei Viazov, Olena Brovko, Abdel-Rahman Zekri, Yury Khudyakov, Michael Nassal, Paul Pumpens, Thomas Pietschmann, Jörg Timm, Michael Roggendorf, Andreas Walker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4094522?pdf=render

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