MLN64 induces mitochondrial dysfunction associated with increased mitochondrial cholesterol content
MLN64 is a late endosomal cholesterol-binding membrane protein that has been implicated in cholesterol transport from endosomal membranes to the plasma membrane and/or mitochondria, in toxin-induced resistance, and in mitochondrial dysfunction. Down-regulation of MLN64 in Niemann-Pick C1 deficient c...
Main Authors: | Elisa Balboa, Juan Castro, María-José Pinochet, Gonzalo I. Cancino, Nuria Matías, Pablo José Sáez, Alexis Martínez, Alejandra R. Álvarez, Carmen Garcia-Ruiz, José C. Fernandez-Checa, Silvana Zanlungo |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-08-01
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Series: | Redox Biology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231716304645 |
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