Synergistic effects of brain-derived neurotrophic factor (BDNF) and exercise intensity on memory in the adolescent brain: a commentary
Abstract This commentary highlights the recently published study by Jeon and Ha (Environ Health Prev Med 22:27, 2017) examining the effects of exercise intensity and brain-derived neurotrophic factor (BDNF) on memory in adolescents. This 12-week training study elicited increases in BDNF and improvem...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Komiyama Printing Co. Ltd
2018-04-01
|
| Series: | Environmental Health and Preventive Medicine |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12199-018-0701-8 |
| _version_ | 1818013609000697856 |
|---|---|
| author | Tharmegan Tharmaratnam Tyler Tabobondung Taylor Tabobondung Sally Doherty |
| author_facet | Tharmegan Tharmaratnam Tyler Tabobondung Taylor Tabobondung Sally Doherty |
| author_sort | Tharmegan Tharmaratnam |
| collection | DOAJ |
| description | Abstract This commentary highlights the recently published study by Jeon and Ha (Environ Health Prev Med 22:27, 2017) examining the effects of exercise intensity and brain-derived neurotrophic factor (BDNF) on memory in adolescents. This 12-week training study elicited increases in BDNF and improvements in working memory during moderate- and high-intensity exercise, which may have been achieved through improved brain tissue oxygenation, nutrient delivery, and BDNF mRNA expression. These improvements highlight the positive neuroendocrinological effects of BDNF and its role as a potential candidate molecule, as a mediator of synaptic plasticity. In this commentary, we aim to highlight the strengths and potential areas of consideration of Jeon and Ha (Environ Health Prev Med 22:27, 2017). We also offer insight into the clinical implications of this study, such as advocating for exercise in healthy children and as adjunctive therapy in pathological states. This study is promising and further highlights the importance of cardiorespiratory exercise in improving physiological health and cognitive functioning in youth through the phenomenon of neuroplasticity. |
| first_indexed | 2024-04-14T06:35:22Z |
| format | Article |
| id | doaj.art-494d73e1ff4e419f90307fa432026d66 |
| institution | Directory Open Access Journal |
| issn | 1342-078X 1347-4715 |
| language | English |
| last_indexed | 2024-04-14T06:35:22Z |
| publishDate | 2018-04-01 |
| publisher | Komiyama Printing Co. Ltd |
| record_format | Article |
| series | Environmental Health and Preventive Medicine |
| spelling | doaj.art-494d73e1ff4e419f90307fa432026d662022-12-22T02:07:30ZengKomiyama Printing Co. LtdEnvironmental Health and Preventive Medicine1342-078X1347-47152018-04-012311410.1186/s12199-018-0701-8Synergistic effects of brain-derived neurotrophic factor (BDNF) and exercise intensity on memory in the adolescent brain: a commentaryTharmegan Tharmaratnam0Tyler Tabobondung1Taylor Tabobondung2Sally Doherty3School of Medicine, Royal College of Surgeons in Ireland-Medical University of BahrainBrantford General Hospital, Department of Family Medicine, Michael G. DeGroote School of Medicine, McMaster UniversityDepartment of Physical and Environmental Sciences, University of TorontoSchool of Medicine, Royal College of Surgeons in Ireland-Medical University of BahrainAbstract This commentary highlights the recently published study by Jeon and Ha (Environ Health Prev Med 22:27, 2017) examining the effects of exercise intensity and brain-derived neurotrophic factor (BDNF) on memory in adolescents. This 12-week training study elicited increases in BDNF and improvements in working memory during moderate- and high-intensity exercise, which may have been achieved through improved brain tissue oxygenation, nutrient delivery, and BDNF mRNA expression. These improvements highlight the positive neuroendocrinological effects of BDNF and its role as a potential candidate molecule, as a mediator of synaptic plasticity. In this commentary, we aim to highlight the strengths and potential areas of consideration of Jeon and Ha (Environ Health Prev Med 22:27, 2017). We also offer insight into the clinical implications of this study, such as advocating for exercise in healthy children and as adjunctive therapy in pathological states. This study is promising and further highlights the importance of cardiorespiratory exercise in improving physiological health and cognitive functioning in youth through the phenomenon of neuroplasticity.http://link.springer.com/article/10.1186/s12199-018-0701-8Brain-derived neurotrophic factorMemoryAerobic exerciseNeurogenesisExercise intensityCognition |
| spellingShingle | Tharmegan Tharmaratnam Tyler Tabobondung Taylor Tabobondung Sally Doherty Synergistic effects of brain-derived neurotrophic factor (BDNF) and exercise intensity on memory in the adolescent brain: a commentary Environmental Health and Preventive Medicine Brain-derived neurotrophic factor Memory Aerobic exercise Neurogenesis Exercise intensity Cognition |
| title | Synergistic effects of brain-derived neurotrophic factor (BDNF) and exercise intensity on memory in the adolescent brain: a commentary |
| title_full | Synergistic effects of brain-derived neurotrophic factor (BDNF) and exercise intensity on memory in the adolescent brain: a commentary |
| title_fullStr | Synergistic effects of brain-derived neurotrophic factor (BDNF) and exercise intensity on memory in the adolescent brain: a commentary |
| title_full_unstemmed | Synergistic effects of brain-derived neurotrophic factor (BDNF) and exercise intensity on memory in the adolescent brain: a commentary |
| title_short | Synergistic effects of brain-derived neurotrophic factor (BDNF) and exercise intensity on memory in the adolescent brain: a commentary |
| title_sort | synergistic effects of brain derived neurotrophic factor bdnf and exercise intensity on memory in the adolescent brain a commentary |
| topic | Brain-derived neurotrophic factor Memory Aerobic exercise Neurogenesis Exercise intensity Cognition |
| url | http://link.springer.com/article/10.1186/s12199-018-0701-8 |
| work_keys_str_mv | AT tharmegantharmaratnam synergisticeffectsofbrainderivedneurotrophicfactorbdnfandexerciseintensityonmemoryintheadolescentbrainacommentary AT tylertabobondung synergisticeffectsofbrainderivedneurotrophicfactorbdnfandexerciseintensityonmemoryintheadolescentbrainacommentary AT taylortabobondung synergisticeffectsofbrainderivedneurotrophicfactorbdnfandexerciseintensityonmemoryintheadolescentbrainacommentary AT sallydoherty synergisticeffectsofbrainderivedneurotrophicfactorbdnfandexerciseintensityonmemoryintheadolescentbrainacommentary |