Molecular mechanical differences between isoforms of contractile actin in the presence of isoforms of smooth muscle tropomyosin.
The proteins involved in smooth muscle's molecular contractile mechanism - the anti-parallel motion of actin and myosin filaments driven by myosin heads interacting with actin - are found as different isoforms. While their expression levels are altered in disease states, their relevance to the...
Main Authors: | Lennart Hilbert, Genevieve Bates, Horia N Roman, Jenna L Blumenthal, Nedjma B Zitouni, Apolinary Sobieszek, Michael C Mackey, Anne-Marie Lauzon |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-10-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC3812040?pdf=render |
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