Molecular mechanical differences between isoforms of contractile actin in the presence of isoforms of smooth muscle tropomyosin.

The proteins involved in smooth muscle's molecular contractile mechanism - the anti-parallel motion of actin and myosin filaments driven by myosin heads interacting with actin - are found as different isoforms. While their expression levels are altered in disease states, their relevance to the...

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Bibliographic Details
Main Authors: Lennart Hilbert, Genevieve Bates, Horia N Roman, Jenna L Blumenthal, Nedjma B Zitouni, Apolinary Sobieszek, Michael C Mackey, Anne-Marie Lauzon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-10-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3812040?pdf=render

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