New Latency Reversing Agents for HIV-1 Cure: Insights from Nonhuman Primate Models

New Latency Reversing Agents for HIV-1 Cure: Insights from Nonhuman Primate Models

Antiretroviral therapy (ART) controls human immunodeficiency virus 1 (HIV-1) replication and prevents disease progression but does not eradicate HIV-1. The persistence of a reservoir of latently infected cells represents the main barrier to a cure. “Shock and kill” is a promising strategy involving...

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Bibliographic Details
Main Authors: Katherine M. Bricker, Ann Chahroudi, Maud Mavigner
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Viruses
Subjects:
HIV-1 cure
shock and kill
latency reversing agents
nonhuman primates
Online Access:https://www.mdpi.com/1999-4915/13/8/1560

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