In Situ Focused Beam Reflectance Measurement (FBRM), Attenuated Total Reflectance Fourier Transform Infrared (ATR-FTIR) and Raman Characterization of the Polymorphic Transformation of Carbamazepine

In Situ Focused Beam Reflectance Measurement (FBRM), Attenuated Total Reflectance Fourier Transform Infrared (ATR-FTIR) and Raman Characterization of the Polymorphic Transformation of Carbamazepine

The objective of this work was to study the polymorphic transformation of carbamazepine from Form II to Form III in 1-propanol during seeded isothermal batch crystallization. First, the pure Form II and Form III were obtained and characterized. Then their solubilities and metastable zone limits were...

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Bibliographic Details
Main Authors: Sohrab Rohani, Yingying Zhao, Ying Bao, Jingkang Wang
Format: Article
Language:English
Published: MDPI AG 2012-02-01
Series:Pharmaceutics
Subjects:
carbamazepine
polymorph transformation
in-situ quantitative method
in-situ analytical techniques
Online Access:http://www.mdpi.com/1999-4923/4/1/164/

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