Mononuclear phagocytes and airway epithelial cells: novel sources of matrix metalloproteinase-8 (MMP-8) in patients with idiopathic pulmonary fibrosis.

Mononuclear phagocytes and airway epithelial cells: novel sources of matrix metalloproteinase-8 (MMP-8) in patients with idiopathic pulmonary fibrosis.

OBJECTIVES:Matrix metalloproteinase-8 (MMP-8) promotes lung fibrotic responses to bleomycin in mice. Although prior studies reported that MMP-8 levels are increased in plasma and bronchoalveolar lavage fluid (BALF) samples from IPF patients, neither the bioactive forms nor the cellular sources of MM...

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Bibliographic Details
Main Authors: Vanessa J Craig, Francesca Polverino, Maria E Laucho-Contreras, Yuanyuan Shi, Yushi Liu, Juan C Osorio, Yohannes Tesfaigzi, Victor Pinto-Plata, Bernadette R Gochuico, Ivan O Rosas, Caroline A Owen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4020836?pdf=render

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http://europepmc.org/articles/PMC4020836?pdf=render

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