Pre- and Postnatal Vitamin D Status and Allergy Outcomes in Early Childhood
The dramatic increase in the prevalence of allergic disease in recent decades reflects environmental and behavioural changes that have altered patterns of early immune development. The very early onset of allergic diseases points to the specific vulnerability of the developing immune system to envir...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-04-01
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| Series: | Biomedicines |
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| Online Access: | https://www.mdpi.com/2227-9059/10/5/933 |
| _version_ | 1827670175908888576 |
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| author | Kristina Rueter Aris Siafarikas Debra J. Palmer Susan L. Prescott |
| author_facet | Kristina Rueter Aris Siafarikas Debra J. Palmer Susan L. Prescott |
| author_sort | Kristina Rueter |
| collection | DOAJ |
| description | The dramatic increase in the prevalence of allergic disease in recent decades reflects environmental and behavioural changes that have altered patterns of early immune development. The very early onset of allergic diseases points to the specific vulnerability of the developing immune system to environmental changes and the development of primary intervention strategies is crucial to address this unparalleled burden. Vitamin D is known to have immunomodulatory functions. While allergic disease is multifactorial, associations with reduced sunlight exposure have led to the hypothesis that suboptimal vitamin D levels during critical early periods may be one possible explanation. Interventions to improve vitamin D status, especially in early life, may be the key to allergic disease prevention. |
| first_indexed | 2024-03-10T03:18:19Z |
| format | Article |
| id | doaj.art-495df46aa2934c5dbca9a9f4634f797d |
| institution | Directory Open Access Journal |
| issn | 2227-9059 |
| language | English |
| last_indexed | 2024-03-10T03:18:19Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj.art-495df46aa2934c5dbca9a9f4634f797d2023-11-23T10:08:40ZengMDPI AGBiomedicines2227-90592022-04-0110593310.3390/biomedicines10050933Pre- and Postnatal Vitamin D Status and Allergy Outcomes in Early ChildhoodKristina Rueter0Aris Siafarikas1Debra J. Palmer2Susan L. Prescott3School of Medicine, The University of Western Australia, 35 Stirling Highway, Crawley 6009, AustraliaSchool of Medicine, The University of Western Australia, 35 Stirling Highway, Crawley 6009, AustraliaSchool of Medicine, The University of Western Australia, 35 Stirling Highway, Crawley 6009, AustraliaSchool of Medicine, The University of Western Australia, 35 Stirling Highway, Crawley 6009, AustraliaThe dramatic increase in the prevalence of allergic disease in recent decades reflects environmental and behavioural changes that have altered patterns of early immune development. The very early onset of allergic diseases points to the specific vulnerability of the developing immune system to environmental changes and the development of primary intervention strategies is crucial to address this unparalleled burden. Vitamin D is known to have immunomodulatory functions. While allergic disease is multifactorial, associations with reduced sunlight exposure have led to the hypothesis that suboptimal vitamin D levels during critical early periods may be one possible explanation. Interventions to improve vitamin D status, especially in early life, may be the key to allergic disease prevention.https://www.mdpi.com/2227-9059/10/5/933vitamin Dnon-communicable diseaseallergic diseasepregnancyinfancyearly childhood |
| spellingShingle | Kristina Rueter Aris Siafarikas Debra J. Palmer Susan L. Prescott Pre- and Postnatal Vitamin D Status and Allergy Outcomes in Early Childhood Biomedicines vitamin D non-communicable disease allergic disease pregnancy infancy early childhood |
| title | Pre- and Postnatal Vitamin D Status and Allergy Outcomes in Early Childhood |
| title_full | Pre- and Postnatal Vitamin D Status and Allergy Outcomes in Early Childhood |
| title_fullStr | Pre- and Postnatal Vitamin D Status and Allergy Outcomes in Early Childhood |
| title_full_unstemmed | Pre- and Postnatal Vitamin D Status and Allergy Outcomes in Early Childhood |
| title_short | Pre- and Postnatal Vitamin D Status and Allergy Outcomes in Early Childhood |
| title_sort | pre and postnatal vitamin d status and allergy outcomes in early childhood |
| topic | vitamin D non-communicable disease allergic disease pregnancy infancy early childhood |
| url | https://www.mdpi.com/2227-9059/10/5/933 |
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