Appraisal of Bioactive Compounds of Betel Fruit as Antimalarial Agents by Targeting Plasmepsin 1 and 2: A Computational Approach

Appraisal of Bioactive Compounds of Betel Fruit as Antimalarial Agents by Targeting Plasmepsin 1 and 2: A Computational Approach

In many countries, the fruit of betel (<i>Piper betle</i> Linn) is traditionally used as medicine for treating malaria. It is a fatal disease, and existing medications are rapidly losing potency, necessitating the development of innovative pharmaceutics. The current study attempted to de...

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Bibliographic Details
Main Authors: Fatimawali, Trina Ekawati Tallei, Billy Johnson Kepel, Mohammed Alorabi, Ahmed M. El-Shehawi, Widdhi Bodhi, Sefren Geiner Tumilaar, Ismail Celik, Gomaa Mostafa-Hedeab, Amany Abdel-Rahman Mohamed, Talha Bin Emran
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Pharmaceuticals
Subjects:
<i>Piper betle</i>
betel fruit
malaria
in silico
protease inhibitor
plasmepsin
Online Access:https://www.mdpi.com/1424-8247/14/12/1285

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