Trichinella spiralis: impact on the expression of Toll-like receptor 4 (TLR4) gene during the intestinal phase of experimental trichinellosis

Introduction: Toll-like receptors (TLRs) play a key role in the rapid activation of the innate immune response to a variety of pathogens. The aim of this study was to evaluate the effect of Trichinella spiralis infection on the level of expression of the tlr4 gene in mouse intestines during the inte...

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Main Authors: Wojtkowiak-Giera Agnieszka, Wandurska-Nowak Elżbieta, Derda Monika, Jankowska Wiesława, Jagodziński Paweł P., Hadaś Edward
Format: Article
Language:English
Published: Sciendo 2018-12-01
Series:Journal of Veterinary Research
Subjects:
Online Access:https://doi.org/10.2478/jvetres-2018-0063
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author Wojtkowiak-Giera Agnieszka
Wandurska-Nowak Elżbieta
Derda Monika
Jankowska Wiesława
Jagodziński Paweł P.
Hadaś Edward
author_facet Wojtkowiak-Giera Agnieszka
Wandurska-Nowak Elżbieta
Derda Monika
Jankowska Wiesława
Jagodziński Paweł P.
Hadaś Edward
author_sort Wojtkowiak-Giera Agnieszka
collection DOAJ
description Introduction: Toll-like receptors (TLRs) play a key role in the rapid activation of the innate immune response to a variety of pathogens. The aim of this study was to evaluate the effect of Trichinella spiralis infection on the level of expression of the tlr4 gene in mouse intestines during the intestinal phase of experimental trichinellosis.
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spelling doaj.art-4969e2d2faa64dce8dca21d880beda2d2022-12-21T21:27:41ZengSciendoJournal of Veterinary Research2450-86082018-12-0162449349610.2478/jvetres-2018-0063jvetres-2018-0063Trichinella spiralis: impact on the expression of Toll-like receptor 4 (TLR4) gene during the intestinal phase of experimental trichinellosisWojtkowiak-Giera Agnieszka0Wandurska-Nowak Elżbieta1Derda Monika2Jankowska Wiesława3Jagodziński Paweł P.4Hadaś Edward5Department of Biology and Medical Parasitology, Poznan University of Medical Sciences, 61-701Poznan, PolandDepartment of Biology and Medical Parasitology, Poznan University of Medical Sciences, 61-701Poznan, PolandDepartment of Biology and Medical Parasitology, Poznan University of Medical Sciences, 61-701Poznan, PolandDepartment of Biology and Medical Parasitology, Poznan University of Medical Sciences, 61-701Poznan, PolandDepartment of Biochemistry and Molecular Biology, Poznan University of Medical Sciences, 60-781 Poznan, PolandDepartment of Biology and Medical Parasitology, Poznan University of Medical Sciences, 61-701Poznan, PolandIntroduction: Toll-like receptors (TLRs) play a key role in the rapid activation of the innate immune response to a variety of pathogens. The aim of this study was to evaluate the effect of Trichinella spiralis infection on the level of expression of the tlr4 gene in mouse intestines during the intestinal phase of experimental trichinellosis.https://doi.org/10.2478/jvetres-2018-0063mouseintestinestrichinellosistoll-like receptor 4q-pcrimmunohistochemical staining
spellingShingle Wojtkowiak-Giera Agnieszka
Wandurska-Nowak Elżbieta
Derda Monika
Jankowska Wiesława
Jagodziński Paweł P.
Hadaś Edward
Trichinella spiralis: impact on the expression of Toll-like receptor 4 (TLR4) gene during the intestinal phase of experimental trichinellosis
Journal of Veterinary Research
mouse
intestines
trichinellosis
toll-like receptor 4
q-pcr
immunohistochemical staining
title Trichinella spiralis: impact on the expression of Toll-like receptor 4 (TLR4) gene during the intestinal phase of experimental trichinellosis
title_full Trichinella spiralis: impact on the expression of Toll-like receptor 4 (TLR4) gene during the intestinal phase of experimental trichinellosis
title_fullStr Trichinella spiralis: impact on the expression of Toll-like receptor 4 (TLR4) gene during the intestinal phase of experimental trichinellosis
title_full_unstemmed Trichinella spiralis: impact on the expression of Toll-like receptor 4 (TLR4) gene during the intestinal phase of experimental trichinellosis
title_short Trichinella spiralis: impact on the expression of Toll-like receptor 4 (TLR4) gene during the intestinal phase of experimental trichinellosis
title_sort trichinella spiralis impact on the expression of toll like receptor 4 tlr4 gene during the intestinal phase of experimental trichinellosis
topic mouse
intestines
trichinellosis
toll-like receptor 4
q-pcr
immunohistochemical staining
url https://doi.org/10.2478/jvetres-2018-0063
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