Polyphyllin VII alleviates pulmonary hypertension by inducing miR-205–5p to target the β-catenin pathway

Polyphyllin VII alleviates pulmonary hypertension by inducing miR-205–5p to target the β-catenin pathway

Objective: This study aims to investigate the impact of Polyphyllin VII (PP7) on pulmonary hypertension (PH) and elucidate the underlying mechanism involving microRNA (miR)−205–5p/β-catenin. Methods: The PH rat model was induced through hypoxia exposure. The effects of intraperitoneal injection of P...

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Bibliographic Details
Main Authors: Fangyun Zhao, Chunhong Pan, Yue Zhang, Jiao Yang, Xiqian Xing
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Polyphyllin VII
Pulmonary hypertension
MicroRNA-205–5p
β-catenin
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223013148

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