Prior dengue virus serotype 3 infection modulates subsequent plasmablast responses to Zika virus infection in rhesus macaques

Prior dengue virus serotype 3 infection modulates subsequent plasmablast responses to Zika virus infection in rhesus macaques

ABSTRACTImmunodominant and highly conserved flavivirus envelope proteins can trigger cross-reactive IgG antibodies against related flaviviruses, which shapes subsequent protection or disease severity. This study examined how prior dengue serotype 3 (DENV-3) infection affects subsequent Zika virus (Z...

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Bibliographic Details
Main Authors: Tulika Singh, Itzayana G. Miller, Sravani Venkatayogi, Helen Webster, Holly J. Heimsath, Josh A. Eudailey, Dawn M. Dudley, Amit Kumar, Riley J. Mangan, Amelia Thein, Matthew T. Aliota, Christina M. Newman, Mariel S. Mohns, Meghan E. Breitbach, Madison Berry, Thomas C. Friedrich, Kevin Wiehe, David H. O'Connor, Sallie R. Permar
Format: Article
Language:English
Published: American Society for Microbiology 2024-03-01
Series:mBio
Subjects:
Zika virus
dengue virus
plasmablast
B cell
neutralizing antibodies
Online Access:https://journals.asm.org/doi/10.1128/mbio.03160-23

Internet

https://journals.asm.org/doi/10.1128/mbio.03160-23

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