Role and mechanism of DNA methylation and its inhibitors in hepatic fibrosis

Role and mechanism of DNA methylation and its inhibitors in hepatic fibrosis

Liver fibrosis is a repair response to injury caused by various chronic stimuli that continually act on the liver. Among them, the activation of hepatic stellate cells (HSCs) and their transformation into a myofibroblast phenotype is a key event leading to liver fibrosis, however the mechanism has n...

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Bibliographic Details
Main Authors:	Shi-Yi Lyu, Wang Xiao, Guang-Zu Cui, Cheng Yu, Huan Liu, Min Lyu, Qian-Ya Kuang, En-Hua Xiao, Yong-Heng Luo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-03-01
Series:	Frontiers in Genetics
Subjects:	hepatic fibrosis DNA methylation epigenetics hepatic stellate cells (HSCs) DNA methylation inhibitors
Online Access:	https://www.frontiersin.org/articles/10.3389/fgene.2023.1124330/full

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