Pituitary metastasis of hepatocellular carcinoma as the initial presentations: a case report and review of the literature
BackgroundExtrahepatic metastasis of hepatocellular carcinoma (HCC) is common. However, pituitary metastasis of HCC is extremely rare. Our case may be helpful to extend the understanding of the disease.Case presentationA 65-year-old man presented to the outpatient department for unexplained headache...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-07-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2023.1123855/full |
| _version_ | 1827906581514158080 |
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| author | Qiang He Feng Deng Bowen Cai Chao You Songping Zheng |
| author_facet | Qiang He Feng Deng Bowen Cai Chao You Songping Zheng |
| author_sort | Qiang He |
| collection | DOAJ |
| description | BackgroundExtrahepatic metastasis of hepatocellular carcinoma (HCC) is common. However, pituitary metastasis of HCC is extremely rare. Our case may be helpful to extend the understanding of the disease.Case presentationA 65-year-old man presented to the outpatient department for unexplained headache and ptosis for 1 month. Brain imaging showed a slight enhancement tumor in the pituitary fossa, and the endocrinological assessment showed normal results. We considered the tumor as a non-functioning pituitary adenoma before surgery. Then, the tumor was resected by an endonasal endoscopic transsphenoidal approach. The histopathological examination results revealed the pituitary metastasis of HCC. Additional abdominal imaging revealed tumors were located in the left and right liver lobes with portal vein invasion and bilateral ilium metastases. After multidisciplinary cooperation, the patient chose chemotherapy.ConclusionWe report a case of HCC metastasis to the pituitary gland that initially presented with neurological symptoms. We should consider the possibility of pituitary metastasis in HCC patients. |
| first_indexed | 2024-03-13T00:58:54Z |
| format | Article |
| id | doaj.art-49708ef11b294fcda2a6269abc88fd40 |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-03-13T00:58:54Z |
| publishDate | 2023-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-49708ef11b294fcda2a6269abc88fd402023-07-06T13:42:46ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2023-07-011310.3389/fonc.2023.11238551123855Pituitary metastasis of hepatocellular carcinoma as the initial presentations: a case report and review of the literatureQiang He0Feng Deng1Bowen Cai2Chao You3Songping Zheng4Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, ChinaDepartment of Hepatic Surgery, The Second Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, ChinaDepartment of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, ChinaDepartment of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, ChinaDepartment of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, ChinaBackgroundExtrahepatic metastasis of hepatocellular carcinoma (HCC) is common. However, pituitary metastasis of HCC is extremely rare. Our case may be helpful to extend the understanding of the disease.Case presentationA 65-year-old man presented to the outpatient department for unexplained headache and ptosis for 1 month. Brain imaging showed a slight enhancement tumor in the pituitary fossa, and the endocrinological assessment showed normal results. We considered the tumor as a non-functioning pituitary adenoma before surgery. Then, the tumor was resected by an endonasal endoscopic transsphenoidal approach. The histopathological examination results revealed the pituitary metastasis of HCC. Additional abdominal imaging revealed tumors were located in the left and right liver lobes with portal vein invasion and bilateral ilium metastases. After multidisciplinary cooperation, the patient chose chemotherapy.ConclusionWe report a case of HCC metastasis to the pituitary gland that initially presented with neurological symptoms. We should consider the possibility of pituitary metastasis in HCC patients.https://www.frontiersin.org/articles/10.3389/fonc.2023.1123855/fullhepatocellular carcinomapituitary metastasizescase reportheadacheliterature review |
| spellingShingle | Qiang He Feng Deng Bowen Cai Chao You Songping Zheng Pituitary metastasis of hepatocellular carcinoma as the initial presentations: a case report and review of the literature Frontiers in Oncology hepatocellular carcinoma pituitary metastasizes case report headache literature review |
| title | Pituitary metastasis of hepatocellular carcinoma as the initial presentations: a case report and review of the literature |
| title_full | Pituitary metastasis of hepatocellular carcinoma as the initial presentations: a case report and review of the literature |
| title_fullStr | Pituitary metastasis of hepatocellular carcinoma as the initial presentations: a case report and review of the literature |
| title_full_unstemmed | Pituitary metastasis of hepatocellular carcinoma as the initial presentations: a case report and review of the literature |
| title_short | Pituitary metastasis of hepatocellular carcinoma as the initial presentations: a case report and review of the literature |
| title_sort | pituitary metastasis of hepatocellular carcinoma as the initial presentations a case report and review of the literature |
| topic | hepatocellular carcinoma pituitary metastasizes case report headache literature review |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2023.1123855/full |
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