The Influence of CYP3A4 Polymorphism in Sex Steroids as a Risk Factor for Breast Cancer

The Influence of CYP3A4 Polymorphism in Sex Steroids as a Risk Factor for Breast Cancer

Abstract Objective Epidemiological studies have shown evidence of the effect of sex hormones in the pathogenesis of breast cancer, and have suggested a relationship of the disease with variations in genes involved in estrogen synthesis and/or metabolism. The aim of the present study was to evaluate...

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Bibliographic Details
Main Authors: Melissa Gonzalez Veiga, Rogério Tadeu Felizi, Dayane Guerino Reis, Ivo Carelli Filho, Cesar Eduardo Fernandes, Ricardo Peres do Souto, Emerson Oliveira
Format: Article
Language:English
Published: Federação Brasileira das Sociedades de Ginecologia e Obstetrícia 2018-11-01
Series:Revista Brasileira de Ginecologia e Obstetrícia
Subjects:
Cyp3a4
breast cancer
polymorphism
estrogens
genetics
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032018001100699&tlng=en

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