Role of Calcium Levels in Pregnant Women with Pre-Eclampsia and Severe Pre-Eclampsia
Objective: To determine the association between hypocalcemia and pre-eclampsia. Study Design: Case-control study. Place and Duration of Study: Department of Obstetrics Gynaecology, Pak Emirates Military Hospital, Rawalpindi Pakistan, from Jan to Jul 2019. Methodology: A total of 90 women, (4...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Army Medical College Rawalpindi
2023-12-01
|
Series: | Pakistan Armed Forces Medical Journal |
Subjects: | |
Online Access: | https://www.pafmj.org/PAFMJ/article/view/7466 |
_version_ | 1797341006200307712 |
---|---|
author | Sara Khan Nusrat Noor Rabiya Akbar Uzma Urooj Sadaf Zohra Tooba Khan |
author_facet | Sara Khan Nusrat Noor Rabiya Akbar Uzma Urooj Sadaf Zohra Tooba Khan |
author_sort | Sara Khan |
collection | DOAJ |
description |
Objective: To determine the association between hypocalcemia and pre-eclampsia.
Study Design: Case-control study.
Place and Duration of Study: Department of Obstetrics Gynaecology, Pak Emirates Military Hospital, Rawalpindi Pakistan,
from Jan to Jul 2019.
Methodology: A total of 90 women, (45 with pre-eclampsia and 45 with normotensive) aged 18-40 years, were included. In all patients, 5ml of venous blood was collected and sent to an institutional pathology laboratory for serum calcium level
measurement. Hypocalcemia was noted in the patients.
Results: The mean gestational age in the Case-Group was 31.40±1.64 weeks, and in the Control-Group was 31.51±1.69 weeks. The mean BMI in the Case-Group was 24.94±4.39 kg/m2, and in the Control-Group was 24.24±4.61 kg/m2. The mean serum calcium levels in the Case-Group were 5328.73±2638.70 ng/ml, and in the Control-Group were 8630.03±1099.26 ng/ml. In our study, the frequency of hypocalcemia in women with pre-eclampsia (Case Group) was found to be 16(36.56%) compared to only 04(8.89%) in normotensive (Control Group) women with a p-value of 005 and Odds ratio of 5.66 which shows a positive association of hypocalcemia with pre-eclampsia.
Conclusion: This study concluded that the frequency of hypocalcemia in pre-eclampsia women is very high, which shows a
positive association between hypocalcemia and pre-eclampsia.
|
first_indexed | 2024-03-08T10:11:38Z |
format | Article |
id | doaj.art-49716f0e0dec4b7f9a491a24caace0dd |
institution | Directory Open Access Journal |
issn | 0030-9648 2411-8842 |
language | English |
last_indexed | 2024-03-08T10:11:38Z |
publishDate | 2023-12-01 |
publisher | Army Medical College Rawalpindi |
record_format | Article |
series | Pakistan Armed Forces Medical Journal |
spelling | doaj.art-49716f0e0dec4b7f9a491a24caace0dd2024-01-29T08:22:22ZengArmy Medical College RawalpindiPakistan Armed Forces Medical Journal0030-96482411-88422023-12-0173610.51253/pafmj.v73i6.7466Role of Calcium Levels in Pregnant Women with Pre-Eclampsia and Severe Pre-EclampsiaSara Khan0Nusrat Noor1Rabiya Akbar2Uzma Urooj3Sadaf Zohra4Tooba Khan5Department of Obstetrics & Gynecology, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanDepartment of Obstetrics & Gynecology, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanDepartment of Obstetrics & Gynecology, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanDepartment of Obstetrics & Gynecology, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanDepartment of Obstetrics & Gynecology, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanDepartment of Obstetrics & Gynecology, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan Objective: To determine the association between hypocalcemia and pre-eclampsia. Study Design: Case-control study. Place and Duration of Study: Department of Obstetrics Gynaecology, Pak Emirates Military Hospital, Rawalpindi Pakistan, from Jan to Jul 2019. Methodology: A total of 90 women, (45 with pre-eclampsia and 45 with normotensive) aged 18-40 years, were included. In all patients, 5ml of venous blood was collected and sent to an institutional pathology laboratory for serum calcium level measurement. Hypocalcemia was noted in the patients. Results: The mean gestational age in the Case-Group was 31.40±1.64 weeks, and in the Control-Group was 31.51±1.69 weeks. The mean BMI in the Case-Group was 24.94±4.39 kg/m2, and in the Control-Group was 24.24±4.61 kg/m2. The mean serum calcium levels in the Case-Group were 5328.73±2638.70 ng/ml, and in the Control-Group were 8630.03±1099.26 ng/ml. In our study, the frequency of hypocalcemia in women with pre-eclampsia (Case Group) was found to be 16(36.56%) compared to only 04(8.89%) in normotensive (Control Group) women with a p-value of 005 and Odds ratio of 5.66 which shows a positive association of hypocalcemia with pre-eclampsia. Conclusion: This study concluded that the frequency of hypocalcemia in pre-eclampsia women is very high, which shows a positive association between hypocalcemia and pre-eclampsia. https://www.pafmj.org/PAFMJ/article/view/7466Calcium associationHypocalcemiaPre-eclampsia |
spellingShingle | Sara Khan Nusrat Noor Rabiya Akbar Uzma Urooj Sadaf Zohra Tooba Khan Role of Calcium Levels in Pregnant Women with Pre-Eclampsia and Severe Pre-Eclampsia Pakistan Armed Forces Medical Journal Calcium association Hypocalcemia Pre-eclampsia |
title | Role of Calcium Levels in Pregnant Women with Pre-Eclampsia and Severe Pre-Eclampsia |
title_full | Role of Calcium Levels in Pregnant Women with Pre-Eclampsia and Severe Pre-Eclampsia |
title_fullStr | Role of Calcium Levels in Pregnant Women with Pre-Eclampsia and Severe Pre-Eclampsia |
title_full_unstemmed | Role of Calcium Levels in Pregnant Women with Pre-Eclampsia and Severe Pre-Eclampsia |
title_short | Role of Calcium Levels in Pregnant Women with Pre-Eclampsia and Severe Pre-Eclampsia |
title_sort | role of calcium levels in pregnant women with pre eclampsia and severe pre eclampsia |
topic | Calcium association Hypocalcemia Pre-eclampsia |
url | https://www.pafmj.org/PAFMJ/article/view/7466 |
work_keys_str_mv | AT sarakhan roleofcalciumlevelsinpregnantwomenwithpreeclampsiaandseverepreeclampsia AT nusratnoor roleofcalciumlevelsinpregnantwomenwithpreeclampsiaandseverepreeclampsia AT rabiyaakbar roleofcalciumlevelsinpregnantwomenwithpreeclampsiaandseverepreeclampsia AT uzmaurooj roleofcalciumlevelsinpregnantwomenwithpreeclampsiaandseverepreeclampsia AT sadafzohra roleofcalciumlevelsinpregnantwomenwithpreeclampsiaandseverepreeclampsia AT toobakhan roleofcalciumlevelsinpregnantwomenwithpreeclampsiaandseverepreeclampsia |