Role of Calcium Levels in Pregnant Women with Pre-Eclampsia and Severe Pre-Eclampsia

Objective: To determine the association between hypocalcemia and pre-eclampsia. Study Design: Case-control study. Place and Duration of Study: Department of Obstetrics Gynaecology, Pak Emirates Military Hospital, Rawalpindi Pakistan, from Jan to Jul 2019. Methodology: A total of 90 women, (4...

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Main Authors: Sara Khan, Nusrat Noor, Rabiya Akbar, Uzma Urooj, Sadaf Zohra, Tooba Khan
Format: Article
Language:English
Published: Army Medical College Rawalpindi 2023-12-01
Series:Pakistan Armed Forces Medical Journal
Subjects:
Online Access:https://www.pafmj.org/PAFMJ/article/view/7466
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author Sara Khan
Nusrat Noor
Rabiya Akbar
Uzma Urooj
Sadaf Zohra
Tooba Khan
author_facet Sara Khan
Nusrat Noor
Rabiya Akbar
Uzma Urooj
Sadaf Zohra
Tooba Khan
author_sort Sara Khan
collection DOAJ
description Objective: To determine the association between hypocalcemia and pre-eclampsia. Study Design: Case-control study. Place and Duration of Study: Department of Obstetrics Gynaecology, Pak Emirates Military Hospital, Rawalpindi Pakistan, from Jan to Jul 2019. Methodology: A total of 90 women, (45 with pre-eclampsia and 45 with normotensive) aged 18-40 years, were included. In all patients, 5ml of venous blood was collected and sent to an institutional pathology laboratory for serum calcium level measurement. Hypocalcemia was noted in the patients. Results: The mean gestational age in the Case-Group was 31.40±1.64 weeks, and in the Control-Group was 31.51±1.69 weeks. The mean BMI in the Case-Group was 24.94±4.39 kg/m2, and in the Control-Group was 24.24±4.61 kg/m2. The mean serum calcium levels in the Case-Group were 5328.73±2638.70 ng/ml, and in the Control-Group were 8630.03±1099.26 ng/ml. In our study, the frequency of hypocalcemia in women with pre-eclampsia (Case Group) was found to be 16(36.56%) compared to only 04(8.89%) in normotensive (Control Group) women with a p-value of 005 and Odds ratio of 5.66 which shows a positive association of hypocalcemia with pre-eclampsia. Conclusion: This study concluded that the frequency of hypocalcemia in pre-eclampsia women is very high, which shows a positive association between hypocalcemia and pre-eclampsia.
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spelling doaj.art-49716f0e0dec4b7f9a491a24caace0dd2024-01-29T08:22:22ZengArmy Medical College RawalpindiPakistan Armed Forces Medical Journal0030-96482411-88422023-12-0173610.51253/pafmj.v73i6.7466Role of Calcium Levels in Pregnant Women with Pre-Eclampsia and Severe Pre-EclampsiaSara Khan0Nusrat Noor1Rabiya Akbar2Uzma Urooj3Sadaf Zohra4Tooba Khan5Department of Obstetrics & Gynecology, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanDepartment of Obstetrics & Gynecology, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanDepartment of Obstetrics & Gynecology, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanDepartment of Obstetrics & Gynecology, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanDepartment of Obstetrics & Gynecology, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanDepartment of Obstetrics & Gynecology, Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan Objective: To determine the association between hypocalcemia and pre-eclampsia. Study Design: Case-control study. Place and Duration of Study: Department of Obstetrics Gynaecology, Pak Emirates Military Hospital, Rawalpindi Pakistan, from Jan to Jul 2019. Methodology: A total of 90 women, (45 with pre-eclampsia and 45 with normotensive) aged 18-40 years, were included. In all patients, 5ml of venous blood was collected and sent to an institutional pathology laboratory for serum calcium level measurement. Hypocalcemia was noted in the patients. Results: The mean gestational age in the Case-Group was 31.40±1.64 weeks, and in the Control-Group was 31.51±1.69 weeks. The mean BMI in the Case-Group was 24.94±4.39 kg/m2, and in the Control-Group was 24.24±4.61 kg/m2. The mean serum calcium levels in the Case-Group were 5328.73±2638.70 ng/ml, and in the Control-Group were 8630.03±1099.26 ng/ml. In our study, the frequency of hypocalcemia in women with pre-eclampsia (Case Group) was found to be 16(36.56%) compared to only 04(8.89%) in normotensive (Control Group) women with a p-value of 005 and Odds ratio of 5.66 which shows a positive association of hypocalcemia with pre-eclampsia. Conclusion: This study concluded that the frequency of hypocalcemia in pre-eclampsia women is very high, which shows a positive association between hypocalcemia and pre-eclampsia. https://www.pafmj.org/PAFMJ/article/view/7466Calcium associationHypocalcemiaPre-eclampsia
spellingShingle Sara Khan
Nusrat Noor
Rabiya Akbar
Uzma Urooj
Sadaf Zohra
Tooba Khan
Role of Calcium Levels in Pregnant Women with Pre-Eclampsia and Severe Pre-Eclampsia
Pakistan Armed Forces Medical Journal
Calcium association
Hypocalcemia
Pre-eclampsia
title Role of Calcium Levels in Pregnant Women with Pre-Eclampsia and Severe Pre-Eclampsia
title_full Role of Calcium Levels in Pregnant Women with Pre-Eclampsia and Severe Pre-Eclampsia
title_fullStr Role of Calcium Levels in Pregnant Women with Pre-Eclampsia and Severe Pre-Eclampsia
title_full_unstemmed Role of Calcium Levels in Pregnant Women with Pre-Eclampsia and Severe Pre-Eclampsia
title_short Role of Calcium Levels in Pregnant Women with Pre-Eclampsia and Severe Pre-Eclampsia
title_sort role of calcium levels in pregnant women with pre eclampsia and severe pre eclampsia
topic Calcium association
Hypocalcemia
Pre-eclampsia
url https://www.pafmj.org/PAFMJ/article/view/7466
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