RFRP-3, the Mammalian Ortholog of GnIH, Is a Novel Modulator Involved in Food Intake and Glucose Homeostasis

RFRP-3, the Mammalian Ortholog of GnIH, Is a Novel Modulator Involved in Food Intake and Glucose Homeostasis

RF amide-related peptide 3 (RFRP-3) is a reproductive inhibitor and an endogenous orexigenic neuropeptide that may be involved in energy homeostasis. In this study, we evaluated the effect of acute or chronic RFRP-3 treatment (administered via intraperitoneal injection) on the food intake, meal micr...

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Bibliographic Details
Main Authors: Konglin Huo, Xun Li, Wen Hu, Xingxing Song, Duoni Zhang, Xin Zhang, Xinyi Chen, Jingzhi Yuan, Jianyu Zuo, Xiaoye Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Endocrinology
Subjects:
RFamide-related peptide-3 (RFRP-3)
food intake
insulin
glucagon
insulin resistance
glucose metabolism
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00194/full

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