Mechanical properties measured by atomic force microscopy define health biomarkers in ageing C. elegans
The development of reliable measures of health in ageing organisms is a need in ageing research. Using atomic force microscopy, here, the authors assess whole body stiffness of worms and show that it reflects organismal fitness.
Main Authors: | Clara L. Essmann, Daniel Martinez-Martinez, Rosina Pryor, Kit-Yi Leung, Kalaivani Bala Krishnan, Prudence Pokway Lui, Nicholas D. E. Greene, André E. X. Brown, Vijay M. Pawar, Mandayam A. Srinivasan, Filipe Cabreiro |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2020-02-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-14785-0 |
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