Construction of a Lactate-Related Prognostic Signature for Predicting Prognosis, Tumor Microenvironment, and Immune Response in Kidney Renal Clear Cell Carcinoma

Construction of a Lactate-Related Prognostic Signature for Predicting Prognosis, Tumor Microenvironment, and Immune Response in Kidney Renal Clear Cell Carcinoma

Kidney renal clear cell carcinoma (KIRC) is one of the most prevalent primary malignancies with high heterogeneity in the urological system. Growing evidence implies that lactate is a significant carbon source for cell metabolism and plays a vital role in tumor development, maintenance, and therapeu...

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Bibliographic Details
Main Authors: Zhuolun Sun, Wen Tao, Xudong Guo, Changying Jing, Mingxiao Zhang, Zhenqing Wang, Feng Kong, Ning Suo, Shaobo Jiang, Hanbo Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Immunology
Subjects:
kidney renal clear cell carcinoma
lactate
nomogram
prognostic signature
tumor microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.818984/full

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