Nutrient sensing via mTOR in T cells maintains a tolerogenic microenvironment

We have proposed that tolerance can be maintained by the induction, by Treg cells, of a tolerogenic microenvironment within tolerated tissues that inhibits effector cell activity but which supports the generation of further Treg cells by infectious tolerance. Two important components of this tolero...

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Bibliographic Details
Main Authors: Duncan eHowie, Herman eWaldmann, Stephen Paul Cobbold
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00409/full

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