Nutrient sensing via mTOR in T cells maintains a tolerogenic microenvironment
We have proposed that tolerance can be maintained by the induction, by Treg cells, of a tolerogenic microenvironment within tolerated tissues that inhibits effector cell activity but which supports the generation of further Treg cells by infectious tolerance. Two important components of this tolero...
Main Authors: | Duncan eHowie, Herman eWaldmann, Stephen Paul Cobbold |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2014-08-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00409/full |
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