Molecularly Targeted Photothermal Ablation of Epidermal Growth Factor Receptor-Expressing Cancer Cells with a Polypyrrole–Iron Oxide–Afatinib Nanocomposite

Molecularly Targeted Photothermal Ablation of Epidermal Growth Factor Receptor-Expressing Cancer Cells with a Polypyrrole–Iron Oxide–Afatinib Nanocomposite

Near-infrared–photothermal therapy (NIR-PTT) is a potential modality for cancer treatment. Directing photothermal effects specifically to cancer cells may enhance the therapeutic index for the best treatment outcome. While epithelial growth factor receptor (EGFR) is commonly overexpressed/geneticall...

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Bibliographic Details
Main Authors: Lekshmi Rethi, Chinmaya Mutalik, Lekha Rethi, Wei-Hung Chiang, Hsin-Lun Lee, Wen-Yu Pan, Tze-Sen Yang, Jeng-Fong Chiou, Yin-Ju Chen, Er-Yuan Chuang, Long-Sheng Lu
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Cancers
Subjects:
polypyrrole
iron oxide
afatinib
EGFR
photothermal therapy
Online Access:https://www.mdpi.com/2072-6694/14/20/5043

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