Campylobacter jejuni sequence types show remarkable spatial and temporal stability in Blackbirds
Background: The zoonotic bacterium Campylobacter jejuni has a broad host range but is especially associated with birds, both domestic and wild. Earlier studies have indicated thrushes of the genus Turdus in Europe to be frequently colonized with C. jejuni, and predominately with host-associated spec...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2015-12-01
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| Series: | Infection Ecology & Epidemiology |
| Subjects: | |
| Online Access: | http://www.infectionecologyandepidemiology.net/index.php/iee/article/view/28383/pdf_42 |
| _version_ | 1818671972355145728 |
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| author | Petra Griekspoor Philip M. Hansbro Jonas Waldenström Björn Olsen |
| author_facet | Petra Griekspoor Philip M. Hansbro Jonas Waldenström Björn Olsen |
| author_sort | Petra Griekspoor |
| collection | DOAJ |
| description | Background: The zoonotic bacterium Campylobacter jejuni has a broad host range but is especially associated with birds, both domestic and wild. Earlier studies have indicated thrushes of the genus Turdus in Europe to be frequently colonized with C. jejuni, and predominately with host-associated specific genotypes. The European Blackbird Turdus merula has a large distribution in Europe, including some oceanic islands, and was also introduced to Australia by European immigrants in the 1850s. Methods: The host specificity and temporal stability of European Blackbird C. jejuni was investigated with multilocus sequence typing in a set of isolates collected from Sweden, Australia, and The Azores. Results: Remarkably, we found that the Swedish, Australian, and Azorean isolates were genetically highly similar, despite extensive spatial and temporal isolation. This indicates adaptation, exquisite specificity, and stability in time for European Blackbirds, which is in sharp contrast with the high levels of recombination and mutation found in poultry-related C. jejuni genotypes. Conclusion: The maintenance of host-specific signals in spatially and temporally separated C. jejuni populations suggests the existence of strong purifying selection for this bacterium in European Blackbirds. |
| first_indexed | 2024-12-17T07:32:29Z |
| format | Article |
| id | doaj.art-498b8241c16b4e18ab222cc9b4c2e836 |
| institution | Directory Open Access Journal |
| issn | 2000-8686 |
| language | English |
| last_indexed | 2024-12-17T07:32:29Z |
| publishDate | 2015-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Infection Ecology & Epidemiology |
| spelling | doaj.art-498b8241c16b4e18ab222cc9b4c2e8362022-12-21T21:58:26ZengTaylor & Francis GroupInfection Ecology & Epidemiology2000-86862015-12-01501510.3402/iee.v5.2838328383Campylobacter jejuni sequence types show remarkable spatial and temporal stability in BlackbirdsPetra Griekspoor0Philip M. Hansbro1Jonas Waldenström2Björn Olsen3 Section for Zoonotic Ecology and Epidemiology, Centre for Ecology and Evolution in Microbial Model Systems (EEMiS), School of Natural Sciences, Linnaeus University, Kalmar, Sweden Centre for Asthma and Respiratory Disease, Hunter Medical Research Institute, University of Newcastle, Newcastle, Australia Section for Zoonotic Ecology and Epidemiology, Centre for Ecology and Evolution in Microbial Model Systems (EEMiS), School of Natural Sciences, Linnaeus University, Kalmar, Sweden Section of Infectious Diseases, Department of Medical Sciences, Uppsala University, Uppsala, SwedenBackground: The zoonotic bacterium Campylobacter jejuni has a broad host range but is especially associated with birds, both domestic and wild. Earlier studies have indicated thrushes of the genus Turdus in Europe to be frequently colonized with C. jejuni, and predominately with host-associated specific genotypes. The European Blackbird Turdus merula has a large distribution in Europe, including some oceanic islands, and was also introduced to Australia by European immigrants in the 1850s. Methods: The host specificity and temporal stability of European Blackbird C. jejuni was investigated with multilocus sequence typing in a set of isolates collected from Sweden, Australia, and The Azores. Results: Remarkably, we found that the Swedish, Australian, and Azorean isolates were genetically highly similar, despite extensive spatial and temporal isolation. This indicates adaptation, exquisite specificity, and stability in time for European Blackbirds, which is in sharp contrast with the high levels of recombination and mutation found in poultry-related C. jejuni genotypes. Conclusion: The maintenance of host-specific signals in spatially and temporally separated C. jejuni populations suggests the existence of strong purifying selection for this bacterium in European Blackbirds.http://www.infectionecologyandepidemiology.net/index.php/iee/article/view/28383/pdf_42gastrointestinal pathogenCampylobacter jejuniBlackbirdMLSTpopulation structure |
| spellingShingle | Petra Griekspoor Philip M. Hansbro Jonas Waldenström Björn Olsen Campylobacter jejuni sequence types show remarkable spatial and temporal stability in Blackbirds Infection Ecology & Epidemiology gastrointestinal pathogen Campylobacter jejuni Blackbird MLST population structure |
| title | Campylobacter jejuni sequence types show remarkable spatial and temporal stability in Blackbirds |
| title_full | Campylobacter jejuni sequence types show remarkable spatial and temporal stability in Blackbirds |
| title_fullStr | Campylobacter jejuni sequence types show remarkable spatial and temporal stability in Blackbirds |
| title_full_unstemmed | Campylobacter jejuni sequence types show remarkable spatial and temporal stability in Blackbirds |
| title_short | Campylobacter jejuni sequence types show remarkable spatial and temporal stability in Blackbirds |
| title_sort | campylobacter jejuni sequence types show remarkable spatial and temporal stability in blackbirds |
| topic | gastrointestinal pathogen Campylobacter jejuni Blackbird MLST population structure |
| url | http://www.infectionecologyandepidemiology.net/index.php/iee/article/view/28383/pdf_42 |
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