Fertility outcome of patients with CBAVD: a single-institution experience
Background and objective: Congenital bilateral absence of the vas deferens (CBAVD) is not common and fertility outcome is not clear. This study is to report fertility outcomes of infertile male with CBAVD. Material and methods: Our study cohort comprised CBAVD males who were enrolled from 2005 to 20...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MRE Press
2022-03-01
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| Series: | Journal of Men's Health |
| Subjects: | |
| Online Access: | https://www.imrpress.com/journal/JOMH/18/4/10.31083/jomh.2021.120 |
| _version_ | 1797326714396737536 |
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| author | Chengquan Ma Zhengyi Sun Jing Wang Binbin Wang Hongjun Li |
| author_facet | Chengquan Ma Zhengyi Sun Jing Wang Binbin Wang Hongjun Li |
| author_sort | Chengquan Ma |
| collection | DOAJ |
| description | Background and objective: Congenital bilateral absence of the vas deferens (CBAVD) is not common and fertility outcome is not clear. This study is to report fertility outcomes of infertile male with CBAVD. Material and methods: Our study cohort comprised CBAVD males who were enrolled from 2005 to 2019. Baseline information was collected including mean age, previous medical history, duration of infertility, sex hormone assays, ejaculate volume/pH, parameters of sperm retrieved by percutaneous epididymal sperm aspiration (PESA), development of seminal vesicle TRUS, follow up fertility outcomes of the patients with intracytoplasmic sperm injection (ICSI) and compared the impact of varies male factors on fertility outcomes. Results: 172 participants with CBAVD were analyzed. A total of 211 ICSI cycles were performed and the live birth rate was 46.92%. Among 126 live births, 57 (45.24%) were boy and 69 (54.76%) were girl. The neonatal weight and height are 3036.83 ± 672.17 g, 49.43 ± 2.49 cm, respectively. There were no significant differences between successes group of couples and fail group of couples for first ICSI cycles cases in terms of age (P = 0.09), testicle volume (left P = 0.96, right P = 0.41), sex hormones (P > 0.05), ejaculate volume (P = 0.79), ejaculate pH (P = 0.78) or sperm quality parameters from PESA (P > 0.05). Conclusions: This study indicates that the clinical characteristics of male with CBAVD had no impact on fertility outcomes. |
| first_indexed | 2024-03-08T06:27:10Z |
| format | Article |
| id | doaj.art-498dbea72bd54426b3ab695f0e73396b |
| institution | Directory Open Access Journal |
| issn | 1875-6859 |
| language | English |
| last_indexed | 2024-03-08T06:27:10Z |
| publishDate | 2022-03-01 |
| publisher | MRE Press |
| record_format | Article |
| series | Journal of Men's Health |
| spelling | doaj.art-498dbea72bd54426b3ab695f0e73396b2024-02-03T13:29:48ZengMRE PressJournal of Men's Health1875-68592022-03-011848010.31083/jomh.2021.120S1875-6867(22)00312-8Fertility outcome of patients with CBAVD: a single-institution experienceChengquan Ma0Zhengyi Sun1Jing Wang2Binbin Wang3Hongjun Li4Department of Urology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, 100730 Beijing, ChinaDepartment of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, 100730 Beijing, ChinaDepartment of Medical Genetics and Developmental Biology, School of Basic Medical Sciences, Capital Medical University, 100069 Beijing, ChinaCenter for Genetics, National Research Institute for Family Planning, 100081 Beijing, ChinaDepartment of Urology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, 100730 Beijing, ChinaBackground and objective: Congenital bilateral absence of the vas deferens (CBAVD) is not common and fertility outcome is not clear. This study is to report fertility outcomes of infertile male with CBAVD. Material and methods: Our study cohort comprised CBAVD males who were enrolled from 2005 to 2019. Baseline information was collected including mean age, previous medical history, duration of infertility, sex hormone assays, ejaculate volume/pH, parameters of sperm retrieved by percutaneous epididymal sperm aspiration (PESA), development of seminal vesicle TRUS, follow up fertility outcomes of the patients with intracytoplasmic sperm injection (ICSI) and compared the impact of varies male factors on fertility outcomes. Results: 172 participants with CBAVD were analyzed. A total of 211 ICSI cycles were performed and the live birth rate was 46.92%. Among 126 live births, 57 (45.24%) were boy and 69 (54.76%) were girl. The neonatal weight and height are 3036.83 ± 672.17 g, 49.43 ± 2.49 cm, respectively. There were no significant differences between successes group of couples and fail group of couples for first ICSI cycles cases in terms of age (P = 0.09), testicle volume (left P = 0.96, right P = 0.41), sex hormones (P > 0.05), ejaculate volume (P = 0.79), ejaculate pH (P = 0.78) or sperm quality parameters from PESA (P > 0.05). Conclusions: This study indicates that the clinical characteristics of male with CBAVD had no impact on fertility outcomes.https://www.imrpress.com/journal/JOMH/18/4/10.31083/jomh.2021.120male infertilitycbavdfertility outcomepercutaneous epididymal sperm aspirationintracytoplasmic sperm injection |
| spellingShingle | Chengquan Ma Zhengyi Sun Jing Wang Binbin Wang Hongjun Li Fertility outcome of patients with CBAVD: a single-institution experience Journal of Men's Health male infertility cbavd fertility outcome percutaneous epididymal sperm aspiration intracytoplasmic sperm injection |
| title | Fertility outcome of patients with CBAVD: a single-institution experience |
| title_full | Fertility outcome of patients with CBAVD: a single-institution experience |
| title_fullStr | Fertility outcome of patients with CBAVD: a single-institution experience |
| title_full_unstemmed | Fertility outcome of patients with CBAVD: a single-institution experience |
| title_short | Fertility outcome of patients with CBAVD: a single-institution experience |
| title_sort | fertility outcome of patients with cbavd a single institution experience |
| topic | male infertility cbavd fertility outcome percutaneous epididymal sperm aspiration intracytoplasmic sperm injection |
| url | https://www.imrpress.com/journal/JOMH/18/4/10.31083/jomh.2021.120 |
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