Should Perirectal Swab Culture Be Performed in Cases Admitted to the Neonatal Intensive Care Unit? Lessons Learned from the Neonatal Intensive Care Unit
Serial perirectal swabs are used to identify colonization of multidrug-resistant bacteria and prevent spread. The purpose of this study was to determine colonization with carbapenem-resistant Enterobacterales (CRE) and vancomycin-resistant Enterococci (VRE). An additional purpose was to establish wh...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-01-01
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| Series: | Children |
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| Online Access: | https://www.mdpi.com/2227-9067/10/2/187 |
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| author | Aysen Orman Yalcin Celik Guliz Evik Gulden Ersöz Necdet Kuyucu Berfin Ozgokce Ozmen |
| author_facet | Aysen Orman Yalcin Celik Guliz Evik Gulden Ersöz Necdet Kuyucu Berfin Ozgokce Ozmen |
| author_sort | Aysen Orman |
| collection | DOAJ |
| description | Serial perirectal swabs are used to identify colonization of multidrug-resistant bacteria and prevent spread. The purpose of this study was to determine colonization with carbapenem-resistant Enterobacterales (CRE) and vancomycin-resistant Enterococci (VRE). An additional purpose was to establish whether sepsis and epidemic associated with these factors were present in the neonatal intensive care unit (NICU), to which infants with hospital stays exceeding 48 h in an external healthcare center NICU were admitted. Perirectal swab samples were collected in the first 24 h by a trained infection nurse using sterile cotton swabs moistened with 0.9% NaCl from patients admitted to our unit after hospitalization exceeding 48 h in an external center. The primary outcome was positivity in perirectal swab cultures, and the secondary outcomes were whether this caused invasive infection and significant NICU outbreaks. A total of 125 newborns meeting the study criteria referred from external healthcare centers between January 2018 and January 2022 were enrolled. Analysis revealed that CRE constituted 27.2% of perirectal swab positivity and VRE 4.8%, and that one in every 4.4 infants included in the study exhibited perirectal swab positivity. The detection of colonization by these microorganisms, and including them within the scope of surveillance, is an important factor in the prevention of NICU epidemics. |
| first_indexed | 2024-03-11T08:59:50Z |
| format | Article |
| id | doaj.art-49918b7c0f6b4403a007ac6d167059e5 |
| institution | Directory Open Access Journal |
| issn | 2227-9067 |
| language | English |
| last_indexed | 2024-03-11T08:59:50Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj.art-49918b7c0f6b4403a007ac6d167059e52023-11-16T19:47:14ZengMDPI AGChildren2227-90672023-01-0110218710.3390/children10020187Should Perirectal Swab Culture Be Performed in Cases Admitted to the Neonatal Intensive Care Unit? Lessons Learned from the Neonatal Intensive Care UnitAysen Orman0Yalcin Celik1Guliz Evik2Gulden Ersöz3Necdet Kuyucu4Berfin Ozgokce Ozmen5Division of Neonatology, Department of Pediatrics, Mersin University School of Medicine, Mersin 33110, TürkiyeDivision of Neonatology, Department of Pediatrics, Mersin University School of Medicine, Mersin 33110, TürkiyeDepartment of Clinical Microbiology and Infectious Diseases, Mersin University School of Medicine, Mersin 33110, TürkiyeDepartment of Clinical Microbiology and Infectious Diseases, Mersin University School of Medicine, Mersin 33110, TürkiyeDepartment of Pediatric Infectious Disease, Mersin University School of Medicine, Mersin 33110, TürkiyeDepartment of Pediatric Infectious Disease, Mersin University School of Medicine, Mersin 33110, TürkiyeSerial perirectal swabs are used to identify colonization of multidrug-resistant bacteria and prevent spread. The purpose of this study was to determine colonization with carbapenem-resistant Enterobacterales (CRE) and vancomycin-resistant Enterococci (VRE). An additional purpose was to establish whether sepsis and epidemic associated with these factors were present in the neonatal intensive care unit (NICU), to which infants with hospital stays exceeding 48 h in an external healthcare center NICU were admitted. Perirectal swab samples were collected in the first 24 h by a trained infection nurse using sterile cotton swabs moistened with 0.9% NaCl from patients admitted to our unit after hospitalization exceeding 48 h in an external center. The primary outcome was positivity in perirectal swab cultures, and the secondary outcomes were whether this caused invasive infection and significant NICU outbreaks. A total of 125 newborns meeting the study criteria referred from external healthcare centers between January 2018 and January 2022 were enrolled. Analysis revealed that CRE constituted 27.2% of perirectal swab positivity and VRE 4.8%, and that one in every 4.4 infants included in the study exhibited perirectal swab positivity. The detection of colonization by these microorganisms, and including them within the scope of surveillance, is an important factor in the prevention of NICU epidemics.https://www.mdpi.com/2227-9067/10/2/187perirectal swabcarbapenemresistanceenterobacteralesvancomycinenterococci |
| spellingShingle | Aysen Orman Yalcin Celik Guliz Evik Gulden Ersöz Necdet Kuyucu Berfin Ozgokce Ozmen Should Perirectal Swab Culture Be Performed in Cases Admitted to the Neonatal Intensive Care Unit? Lessons Learned from the Neonatal Intensive Care Unit Children perirectal swab carbapenem resistance enterobacterales vancomycin enterococci |
| title | Should Perirectal Swab Culture Be Performed in Cases Admitted to the Neonatal Intensive Care Unit? Lessons Learned from the Neonatal Intensive Care Unit |
| title_full | Should Perirectal Swab Culture Be Performed in Cases Admitted to the Neonatal Intensive Care Unit? Lessons Learned from the Neonatal Intensive Care Unit |
| title_fullStr | Should Perirectal Swab Culture Be Performed in Cases Admitted to the Neonatal Intensive Care Unit? Lessons Learned from the Neonatal Intensive Care Unit |
| title_full_unstemmed | Should Perirectal Swab Culture Be Performed in Cases Admitted to the Neonatal Intensive Care Unit? Lessons Learned from the Neonatal Intensive Care Unit |
| title_short | Should Perirectal Swab Culture Be Performed in Cases Admitted to the Neonatal Intensive Care Unit? Lessons Learned from the Neonatal Intensive Care Unit |
| title_sort | should perirectal swab culture be performed in cases admitted to the neonatal intensive care unit lessons learned from the neonatal intensive care unit |
| topic | perirectal swab carbapenem resistance enterobacterales vancomycin enterococci |
| url | https://www.mdpi.com/2227-9067/10/2/187 |
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