Plasma biomarkers for monitoring brain pathophysiology in FMR1 premutation carriers

Plasma biomarkers for monitoring brain pathophysiology in FMR1 premutation carriers

Premutation carriers have a 55-200 CGG expansion in the fragile X mental retardation 1 (FMR1) gene. Currently, 1.5 million individuals are affected in the United States, and carriers are at risk of developing the late-onset neurodegenerative disorder Fragile X-associated tremor ataxia syndrome (FXTA...

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Bibliographic Details
Main Authors:	Cecilia Giulivi, Eleonora Napoli, Flora Tassone, Julian Halmai, Randi Hagerman
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2016-08-01
Series:	Frontiers in Molecular Neuroscience
Subjects:	Fragile X Syndrome Metabolomics neurodegeneration Mitochondrial dysfunction Trinucleotide repeat diseases
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00071/full

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