Essential Oils and Their Natural Active Compounds Presenting Antifungal Properties

The current rise in invasive fungal infections due to the increase in immunosuppressive therapies is a real concern. Moreover, the emergence of resistant strains induces therapeutic failures. In light of these issues, new classes of antifungals are anticipated. Therefore, the plant kingdom represent...

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Main Authors: Maurine D’agostino, Nicolas Tesse, Jean Pol Frippiat, Marie Machouart, Anne Debourgogne
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/24/20/3713
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author Maurine D’agostino
Nicolas Tesse
Jean Pol Frippiat
Marie Machouart
Anne Debourgogne
author_facet Maurine D’agostino
Nicolas Tesse
Jean Pol Frippiat
Marie Machouart
Anne Debourgogne
author_sort Maurine D’agostino
collection DOAJ
description The current rise in invasive fungal infections due to the increase in immunosuppressive therapies is a real concern. Moreover, the emergence of resistant strains induces therapeutic failures. In light of these issues, new classes of antifungals are anticipated. Therefore, the plant kingdom represents an immense potential of natural resources to exploit for these purposes. The aim of this review is to provide information about the antifungal effect of some important essential oils, and to describe the advances made in determining the mechanism of action more precisely. Finally, the issues of toxicity and resistance of fungi to essential oils will be discussed.
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spelling doaj.art-4993575f478a46eeaeaad61d25d79a9b2022-12-21T19:39:17ZengMDPI AGMolecules1420-30492019-10-012420371310.3390/molecules24203713molecules24203713Essential Oils and Their Natural Active Compounds Presenting Antifungal PropertiesMaurine D’agostino0Nicolas Tesse1Jean Pol Frippiat2Marie Machouart3Anne Debourgogne4Laboratoire Stress Immunité Pathogènes, EA7300, Faculté de Médecine, 9 avenue de la Forêt de Haye, 54505 Vandoeuvre-les-Nancy, FranceSociété Septeos, 12 avenue de la grande armée, 75017 Paris, FranceLaboratoire Stress Immunité Pathogènes, EA7300, Faculté de Médecine, 9 avenue de la Forêt de Haye, 54505 Vandoeuvre-les-Nancy, FranceLaboratoire Stress Immunité Pathogènes, EA7300, Faculté de Médecine, 9 avenue de la Forêt de Haye, 54505 Vandoeuvre-les-Nancy, FranceLaboratoire Stress Immunité Pathogènes, EA7300, Faculté de Médecine, 9 avenue de la Forêt de Haye, 54505 Vandoeuvre-les-Nancy, FranceThe current rise in invasive fungal infections due to the increase in immunosuppressive therapies is a real concern. Moreover, the emergence of resistant strains induces therapeutic failures. In light of these issues, new classes of antifungals are anticipated. Therefore, the plant kingdom represents an immense potential of natural resources to exploit for these purposes. The aim of this review is to provide information about the antifungal effect of some important essential oils, and to describe the advances made in determining the mechanism of action more precisely. Finally, the issues of toxicity and resistance of fungi to essential oils will be discussed.https://www.mdpi.com/1420-3049/24/20/3713essential oilantifungalinvasive fungal infection
spellingShingle Maurine D’agostino
Nicolas Tesse
Jean Pol Frippiat
Marie Machouart
Anne Debourgogne
Essential Oils and Their Natural Active Compounds Presenting Antifungal Properties
Molecules
essential oil
antifungal
invasive fungal infection
title Essential Oils and Their Natural Active Compounds Presenting Antifungal Properties
title_full Essential Oils and Their Natural Active Compounds Presenting Antifungal Properties
title_fullStr Essential Oils and Their Natural Active Compounds Presenting Antifungal Properties
title_full_unstemmed Essential Oils and Their Natural Active Compounds Presenting Antifungal Properties
title_short Essential Oils and Their Natural Active Compounds Presenting Antifungal Properties
title_sort essential oils and their natural active compounds presenting antifungal properties
topic essential oil
antifungal
invasive fungal infection
url https://www.mdpi.com/1420-3049/24/20/3713
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