Interaction of Cationic Carbosilane Dendrimers and Their siRNA Complexes with MCF-7 Cells

Interaction of Cationic Carbosilane Dendrimers and Their siRNA Complexes with MCF-7 Cells

The application of siRNA in gene therapy is mainly limited because of the problems with its transport into cells. Utilization of cationic dendrimers as siRNA carriers seems to be a promising solution in overcoming these issues, due to their positive charge and ability to penetrate cell membranes. Th...

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Bibliographic Details
Main Authors: Kamila Białkowska, Katarzyna Miłowska, Sylwia Michlewska, Paulina Sokołowska, Piotr Komorowski, Tania Lozano-Cruz, Rafael Gomez-Ramirez, Francisco Javier de la Mata, Maria Bryszewska
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
siRNA
carbosilane dendrimers
dendriplexes
nanocarriers
Online Access:https://www.mdpi.com/1422-0067/22/13/7097

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