Photoredox-catalyzed reaction as a powerful tool for rapid natural product Gem -dimethylation modification: discovery of potent anti-cancer agents with improved druggability
Tylophorine has diverse biological activities; however, the stability, solubility, and central nervous system toxicity have severely limited use of tylophorine. The gem -dimethyl group is an organic chemistry functional group that consists of two methyl groups bonded to the same carbon atom. This f...
Main Authors: | Chao Zhang, Yugang Song, Xiuyun Sun, Qianlong Liu, Zhen Li, Shenyi Yin, Jianzhong Jeff Xi, Xin Zhai, Yu Rao |
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Format: | Article |
Language: | English |
Published: |
Compuscript Ltd
2023-09-01
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Series: | Acta Materia Medica |
Online Access: | https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2023-0032 |
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