Effects of a spice-blended honey muffin on salivary inflammation markers in adults with obesity: a feasibility trial
AbstractBackground Obesity is considered a low-grade chronically inflamed state that contributes to communicable chronic diseases. This inflammation may be modulated by consuming spices like turmeric daily. However, few studies have looked at the inclusion of spice within whole foods.Objective The p...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2023-12-01
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| Series: | Annals of Medicine |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/07853890.2023.2245325 |
| _version_ | 1797302137706774528 |
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| author | Sofia Acevedo Jeanette M. Andrade |
| author_facet | Sofia Acevedo Jeanette M. Andrade |
| author_sort | Sofia Acevedo |
| collection | DOAJ |
| description | AbstractBackground Obesity is considered a low-grade chronically inflamed state that contributes to communicable chronic diseases. This inflammation may be modulated by consuming spices like turmeric daily. However, few studies have looked at the inclusion of spice within whole foods.Objective The purpose of this feasibility pre/posttrial was to assess the influence of turmeric in a muffin on salivary IL-6 and CRP in adults who were obese.Methods Participants consumed one, 60-gram muffin containing 3 g turmeric for 10 days. Participants provided a urinary sample at baseline, a 2-ml saliva sample, and a 30-day food frequency and spice consumption questionnaire at baseline and post-trial. A one-sample t-test was conducted using SAS v 9.4 with significance determined at p < 0.05.Results A total of 14 participants, average BMI of 32.16 kg/m2 with 10 identifying as female, completed the trial after 5 dropped due to various reasons. The visit lengths and collection of data with participants adhering to the instructions were deemed a success. There was a significant decrease in salivary IL-6 (p = 0.03) but no statistical difference in salivary CRP (p = 0.46). Participants consumed fruits and vegetables at least once daily, chicken and eggs 5–6 times per week, and beef, pork, and fish at least once per week. Participants consumed chili pepper, garlic, cinnamon, cilantro, and ginger at least once per week. No changes were observed in dietary/spice habits during this trial.Conclusion The feasibility pre/post study revealed that consumption of a muffin with turmeric reduced at least salivary IL-6 in 10 days. Modifications to the study design such as lengthier trial time to assess the impact of this muffin on CRP is necessary prior to implementing larger-scale randomized control trials. |
| first_indexed | 2024-03-07T23:32:28Z |
| format | Article |
| id | doaj.art-49965035fe7d4086bccb1afc4de6cf8b |
| institution | Directory Open Access Journal |
| issn | 0785-3890 1365-2060 |
| language | English |
| last_indexed | 2024-03-07T23:32:28Z |
| publishDate | 2023-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Annals of Medicine |
| spelling | doaj.art-49965035fe7d4086bccb1afc4de6cf8b2024-02-20T11:58:23ZengTaylor & Francis GroupAnnals of Medicine0785-38901365-20602023-12-0155210.1080/07853890.2023.2245325Effects of a spice-blended honey muffin on salivary inflammation markers in adults with obesity: a feasibility trialSofia Acevedo0Jeanette M. Andrade1University of FL Food Science and Human Nutrition Department, Gainesville, FL, USAUniversity of FL Food Science and Human Nutrition Department, Gainesville, FL, USAAbstractBackground Obesity is considered a low-grade chronically inflamed state that contributes to communicable chronic diseases. This inflammation may be modulated by consuming spices like turmeric daily. However, few studies have looked at the inclusion of spice within whole foods.Objective The purpose of this feasibility pre/posttrial was to assess the influence of turmeric in a muffin on salivary IL-6 and CRP in adults who were obese.Methods Participants consumed one, 60-gram muffin containing 3 g turmeric for 10 days. Participants provided a urinary sample at baseline, a 2-ml saliva sample, and a 30-day food frequency and spice consumption questionnaire at baseline and post-trial. A one-sample t-test was conducted using SAS v 9.4 with significance determined at p < 0.05.Results A total of 14 participants, average BMI of 32.16 kg/m2 with 10 identifying as female, completed the trial after 5 dropped due to various reasons. The visit lengths and collection of data with participants adhering to the instructions were deemed a success. There was a significant decrease in salivary IL-6 (p = 0.03) but no statistical difference in salivary CRP (p = 0.46). Participants consumed fruits and vegetables at least once daily, chicken and eggs 5–6 times per week, and beef, pork, and fish at least once per week. Participants consumed chili pepper, garlic, cinnamon, cilantro, and ginger at least once per week. No changes were observed in dietary/spice habits during this trial.Conclusion The feasibility pre/post study revealed that consumption of a muffin with turmeric reduced at least salivary IL-6 in 10 days. Modifications to the study design such as lengthier trial time to assess the impact of this muffin on CRP is necessary prior to implementing larger-scale randomized control trials.https://www.tandfonline.com/doi/10.1080/07853890.2023.2245325Chronic inflammationturmericIL-6cRPobesity |
| spellingShingle | Sofia Acevedo Jeanette M. Andrade Effects of a spice-blended honey muffin on salivary inflammation markers in adults with obesity: a feasibility trial Annals of Medicine Chronic inflammation turmeric IL-6 cRP obesity |
| title | Effects of a spice-blended honey muffin on salivary inflammation markers in adults with obesity: a feasibility trial |
| title_full | Effects of a spice-blended honey muffin on salivary inflammation markers in adults with obesity: a feasibility trial |
| title_fullStr | Effects of a spice-blended honey muffin on salivary inflammation markers in adults with obesity: a feasibility trial |
| title_full_unstemmed | Effects of a spice-blended honey muffin on salivary inflammation markers in adults with obesity: a feasibility trial |
| title_short | Effects of a spice-blended honey muffin on salivary inflammation markers in adults with obesity: a feasibility trial |
| title_sort | effects of a spice blended honey muffin on salivary inflammation markers in adults with obesity a feasibility trial |
| topic | Chronic inflammation turmeric IL-6 cRP obesity |
| url | https://www.tandfonline.com/doi/10.1080/07853890.2023.2245325 |
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