Hydrophobic collapse of trigger factor monomer in solution.

Trigger factor (TF) is a chaperone, found in bacterial cells and chloroplasts, that interacts with nascent polypeptide chains to suppress aggregation. While its crystal structure has been resolved, the solution structure and dynamics are largely unknown. We performed multiple molecular dynamics simu...

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Detalles Bibliográficos
Main Authors: Kushagra Singhal, Jocelyne Vreede, Alireza Mashaghi, Sander J Tans, Peter G Bolhuis
Formato: Artigo
Idioma:English
Publicado: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Acceso en liña:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23565160/?tool=EBI