A village in a dish model system for population-scale hiPSC studies

A village in a dish model system for population-scale hiPSC studies

Abstract The mechanisms by which DNA alleles contribute to disease risk, drug response, and other human phenotypes are highly context-specific, varying across cell types and different conditions. Human induced pluripotent stem cells are uniquely suited to study these context-dependent effects but ce...

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Dettagli Bibliografici
Autori principali: Drew R. Neavin, Angela M. Steinmann, Nona Farbehi, Han Sheng Chiu, Maciej S. Daniszewski, Himanshi Arora, Yasmin Bermudez, Cátia Moutinho, Chia-Ling Chan, Monique Bax, Mubarika Tyebally, Vikkitharan Gnanasambandapillai, Chuan E. Lam, Uyen Nguyen, Damián Hernández, Grace E. Lidgerwood, Robert M. Graham, Alex W. Hewitt, Alice Pébay, Nathan J. Palpant, Joseph E. Powell
Natura: Articolo
Lingua:English
Pubblicazione: Nature Portfolio 2023-06-01
Serie:Nature Communications
Accesso online:https://doi.org/10.1038/s41467-023-38704-1

Accesso online

https://doi.org/10.1038/s41467-023-38704-1

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