Anti-Thyroid Peroxidase Reactivity Is Heightened in Pemphigus Vulgaris and Is Driven by Human Leukocyte Antigen Status and the Absence of Desmoglein Reactivity

Anti-Thyroid Peroxidase Reactivity Is Heightened in Pemphigus Vulgaris and Is Driven by Human Leukocyte Antigen Status and the Absence of Desmoglein Reactivity

Pemphigus vulgaris (PV) belongs to an autoimmune disease cluster that includes autoimmune thyroid disease (AITD), suggesting common mechanisms driving autoimmune susceptibility. Our group has shown that PV patients exhibit significant reactivity to AITD-related anti-thyroid peroxidase (anti-TPO), an...

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Bibliographic Details
Main Authors:	Kristina Seiffert-Sinha, Shahzaib Khan, Kristopher Attwood, John A. Gerlach, Animesh A. Sinha
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-04-01
Series:	Frontiers in Immunology
Subjects:	pemphigus vulgaris anti-thyroid peroxidase antibody anti-thyroglobulin antibody anti-desmoglein antibody human leukocyte antigen
Online Access:	http://journal.frontiersin.org/article/10.3389/fimmu.2018.00625/full

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