The Efficacy of an Energy-Restricted Anti-Inflammatory Diet for the Management of Obesity in Younger Adults
There is growing evidence of the dietary impact on obesity-induced low-grade chronic inflammation and the associated chronic non-communicable diseases modification. We determined changes in body composition and cardiometabolic and inflammatory status of participants with obesity after 24 weeks of a...
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MDPI AG
2020-11-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/12/11/3583 |
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| author | Gordana Kenđel Jovanović Ines Mrakovcic-Sutic Sandra Pavičić Žeželj Branislav Šuša Dario Rahelić Sanja Klobučar Majanović |
| author_facet | Gordana Kenđel Jovanović Ines Mrakovcic-Sutic Sandra Pavičić Žeželj Branislav Šuša Dario Rahelić Sanja Klobučar Majanović |
| author_sort | Gordana Kenđel Jovanović |
| collection | DOAJ |
| description | There is growing evidence of the dietary impact on obesity-induced low-grade chronic inflammation and the associated chronic non-communicable diseases modification. We determined changes in body composition and cardiometabolic and inflammatory status of participants with obesity after 24 weeks of a dietary intervention based on an energy-reduced anti-inflammatory diet and examined the relationship of these changes with changes in the inflammatory potential of the diet. The anthropometric and body composition parameters of 81 participants (average age of 43 years, 74 women) were assessed. Metabolic status was determined using the glycemic and lipid statuses, and the cardiometabolic index and inflammatory status were determined using the concentration of high-sensitivity C-reactive protein (hs-CRP), interleukin 6 (IL-6), and tumor necrosis factor α (TNF-α). The inflammatory potential of the diet was assessed using the Dietary Inflammatory Index (DII<sup>®</sup>). Intervention with an anti-inflammatory diet resulted in a significant reduction in body weight and visceral adipose tissue and caused improvements in the participants’ cardiometabolic and inflammatory statuses. The anti-inflammatory diet was shown to be effective regarding obesity management. The study data could advance current scientific knowledge in the field of inflammation and diet, provide guidelines for obesity management, and find its application in routine clinical practice. |
| first_indexed | 2024-03-10T14:38:46Z |
| format | Article |
| id | doaj.art-49a1d7e590bf4ae0b55a321c658a1dd7 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T14:38:46Z |
| publishDate | 2020-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-49a1d7e590bf4ae0b55a321c658a1dd72023-11-20T21:55:16ZengMDPI AGNutrients2072-66432020-11-011211358310.3390/nu12113583The Efficacy of an Energy-Restricted Anti-Inflammatory Diet for the Management of Obesity in Younger AdultsGordana Kenđel Jovanović0Ines Mrakovcic-Sutic1Sandra Pavičić Žeželj2Branislav Šuša3Dario Rahelić4Sanja Klobučar Majanović5Department of Health Ecology, Teaching Institute of Public Health of Primorsko-goranska County, Krešimirova 52a, 51000 Rijeka, CroatiaDepartment of Physiology, Immunology and Pathophysiology, Faculty of Medicine, University of Rijeka, Braće Branchetta 20/1, 51000 Rijeka, CroatiaDepartment of Health Ecology, Teaching Institute of Public Health of Primorsko-goranska County, Krešimirova 52a, 51000 Rijeka, CroatiaGeneral Hospital Pula, Santoriova 24a, 52100 Pula, CroatiaVuk Vrhovac University Clinic for Diabetes, Endocrinology and Metabolic Diseases, Merkur University Hospital, Dugi dol 4a, 10000 Zagreb, CroatiaDepartment of Endocrinology, Diabetes and Metabolic Diseases, Clinical Hospital Centre Rijeka, Krešimirova 42, 51000 Rijeka, CroatiaThere is growing evidence of the dietary impact on obesity-induced low-grade chronic inflammation and the associated chronic non-communicable diseases modification. We determined changes in body composition and cardiometabolic and inflammatory status of participants with obesity after 24 weeks of a dietary intervention based on an energy-reduced anti-inflammatory diet and examined the relationship of these changes with changes in the inflammatory potential of the diet. The anthropometric and body composition parameters of 81 participants (average age of 43 years, 74 women) were assessed. Metabolic status was determined using the glycemic and lipid statuses, and the cardiometabolic index and inflammatory status were determined using the concentration of high-sensitivity C-reactive protein (hs-CRP), interleukin 6 (IL-6), and tumor necrosis factor α (TNF-α). The inflammatory potential of the diet was assessed using the Dietary Inflammatory Index (DII<sup>®</sup>). Intervention with an anti-inflammatory diet resulted in a significant reduction in body weight and visceral adipose tissue and caused improvements in the participants’ cardiometabolic and inflammatory statuses. The anti-inflammatory diet was shown to be effective regarding obesity management. The study data could advance current scientific knowledge in the field of inflammation and diet, provide guidelines for obesity management, and find its application in routine clinical practice.https://www.mdpi.com/2072-6643/12/11/3583anti-inflammatorycytokinesdietinflammationobesityweight reduction programs |
| spellingShingle | Gordana Kenđel Jovanović Ines Mrakovcic-Sutic Sandra Pavičić Žeželj Branislav Šuša Dario Rahelić Sanja Klobučar Majanović The Efficacy of an Energy-Restricted Anti-Inflammatory Diet for the Management of Obesity in Younger Adults Nutrients anti-inflammatory cytokines diet inflammation obesity weight reduction programs |
| title | The Efficacy of an Energy-Restricted Anti-Inflammatory Diet for the Management of Obesity in Younger Adults |
| title_full | The Efficacy of an Energy-Restricted Anti-Inflammatory Diet for the Management of Obesity in Younger Adults |
| title_fullStr | The Efficacy of an Energy-Restricted Anti-Inflammatory Diet for the Management of Obesity in Younger Adults |
| title_full_unstemmed | The Efficacy of an Energy-Restricted Anti-Inflammatory Diet for the Management of Obesity in Younger Adults |
| title_short | The Efficacy of an Energy-Restricted Anti-Inflammatory Diet for the Management of Obesity in Younger Adults |
| title_sort | efficacy of an energy restricted anti inflammatory diet for the management of obesity in younger adults |
| topic | anti-inflammatory cytokines diet inflammation obesity weight reduction programs |
| url | https://www.mdpi.com/2072-6643/12/11/3583 |
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