Oxidative stress induced by Etoposide anti-cancer chemotherapy drives the emergence of tumor-associated bacteria resistance to fluoroquinolones

Oxidative stress induced by Etoposide anti-cancer chemotherapy drives the emergence of tumor-associated bacteria resistance to fluoroquinolones

Introduction: Antibiotic-resistant bacterial infections, such as Pseudomonas aeruginosa and Staphylococcus aureus, are prevalent in lung cancer patients, resulting in poor clinical outcomes and high mortality. Etoposide (ETO) is an FDA-approved chemotherapy drug that kills cancer cells by damaging D...

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Bibliographic Details
Main Authors: Shan Wang, Shepherd Yuen Chan, Yanlin Deng, Bee Luan Khoo, Song Lin Chua
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Journal of Advanced Research
Subjects:
Microfluidics
Cancer
Mutation
Oxidative stress
Antibiotic resistance
Pseudomonas aeruginosa
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123223000620

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