Synthesis and Antimicrobial Activity of N′-Heteroarylidene-1-adamantylcarbohydrazides and (±)-2-(1-Adamantyl)-4-acetyl-5-[5-(4-substituted phenyl-3-isoxazolyl)]-1,3,4-oxadiazolines

Synthesis and Antimicrobial Activity of N′-Heteroarylidene-1-adamantylcarbohydrazides and (±)-2-(1-Adamantyl)-4-acetyl-5-[5-(4-substituted phenyl-3-isoxazolyl)]-1,3,4-oxadiazolines

The reaction of adamantane-1-carbohydrazide (1) with heterocyclic aldehydes, namely 5-(4-chlorophenyl)isoxazole-3-carboxaldehyde (2a), 5-(4-methylphenyl)isoxazole-3-carboxaldehyde (2b), 5-(4-methoxyphenyl)isoxazole-3-carboxaldehyde (2c), 1H-imidazole-2-carboxaldehyde and 2-butyl-4-chloro-1H-imidazol...

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Bibliographic Details
Main Authors: Abdul-Malek S. Al-Tamimi, Ali A. El-Emam, Mohamed A. Al-Omar, Khalid A. Alrashood
Format: Article
Language:English
Published: MDPI AG 2012-03-01
Series:Molecules
Subjects:
adamantane derivatives
1,3,4-oxadiazoles
isoxazoles
antimicrobial activity
Online Access:http://www.mdpi.com/1420-3049/17/3/3475/

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