Cytotoxic CD4+ T Cells Drive Multiple Sclerosis Progression
Multiple sclerosis (MS) is the leading cause of chronic neurological disability in young adults. The clinical disease course of MS varies greatly between individuals, with some patients progressing much more rapidly than others, making prognosis almost impossible. We previously discovered that cytot...
Main Authors: | Liesbet M. Peeters, Marjan Vanheusden, Veerle Somers, Bart Van Wijmeersch, Piet Stinissen, Bieke Broux, Niels Hellings |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2017-09-01
|
Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fimmu.2017.01160/full |
Similar Items
-
Treg-Resistant Cytotoxic CD4<sup>+</sup> T Cells Dictate T Helper Cells in Their Vicinity: TH17 Skewing and Modulation of Proliferation
by: Cindy Hoeks, et al.
Published: (2021-05-01) -
Compositional changes of B and T cell subtypes during fingolimod treatment in multiple sclerosis patients: a 12-month follow-up study.
by: Nele Claes, et al.
Published: (2014-01-01) -
CD28 null pro-atherogenic CD4 T-cells explain the link between CMV infection and an increased risk of cardiovascular death
by: Pera, Alejandra, et al.
Published: (2018) -
Ocrelizumab Depletes CD20+ T Cells in Multiple Sclerosis Patients
by: Stefan Gingele, et al.
Published: (2018-12-01) -
Prominent epigenetic and transcriptomic changes in CD4+ and CD8+ T cells during and after pregnancy in women with multiple sclerosis and controls
by: Alberto Zenere, et al.
Published: (2023-04-01)