Association of Dietary Quality Indices and Glioma: A Case-Control Study
Background and Objectives: Glioma is the most common primary brain tumor, which mostly occurs in adults and is associated with high mortality. The purpose of this study was to investigate the association of food quality indices and glioma in Iranian adults. Methods: This case-control study was per...
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| Format: | Article |
| Language: | fas |
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Qom University of Medical Sciences
2019-06-01
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| Series: | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum |
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| Online Access: | http://journal.muq.ac.ir/article-1-2260-en.html |
| _version_ | 1818912971761385472 |
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| author | Seyed Mohammad Mousavi Omid Sadeghi Mahdi Shayanfar Ahmad Esmaillzadeh |
| author_facet | Seyed Mohammad Mousavi Omid Sadeghi Mahdi Shayanfar Ahmad Esmaillzadeh |
| author_sort | Seyed Mohammad Mousavi |
| collection | DOAJ |
| description | Background and Objectives: Glioma is the most common primary brain tumor, which mostly occurs in adults and is associated with high mortality. The purpose of this study was to investigate the association of food quality indices and glioma in Iranian adults.
Methods: This case-control study was performed on 128 patients with glioma and 256 healthy individuals (matched for age and gender) in hospitals affiliated to Shahid Beheshti University of Medical Sciences, Tehran, between 2009 and 2011. Dietary assessment was performed using a validated block-format 123-item semi-quantitative food frequency questionnaire. Dietary Indices (DDS, AHEI-2010) were developed based on standard methods. Data were analyzed by independent t-test, Chi-Square and ANOVA.
Results: In this study, after controlling for potential confounders, a significant inverse association was found between DDS and risk of glioma (OR: 0.39, 95% CI: 0.17-0.89). This finding was also seen when further adjustment was made for BMI; so that participants in the highest quartile of DDS, were 59% less likely to have glioma compared to those in the lowest quartile (OR: 0.41, 95% CI: 0.18 - 0.93). In addition, a significant inverse association was found between adherence to AHEI and glioma; such that in the fully adjusted model, the participants in the fourth quartile of AHEI had 62% lower risk of glioma compared to those in the the first quartile (OR: 0.38, 95% CI: 0.17-0.84).
Conclusion: The results of this study showed that following a high-diversity healthy diet is associated with reduction in the risk of glioma. |
| first_indexed | 2024-12-19T23:23:04Z |
| format | Article |
| id | doaj.art-49b49f49368449519694ba53e10ff7b9 |
| institution | Directory Open Access Journal |
| issn | 1735-7799 2008-1375 |
| language | fas |
| last_indexed | 2024-12-19T23:23:04Z |
| publishDate | 2019-06-01 |
| publisher | Qom University of Medical Sciences |
| record_format | Article |
| series | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum |
| spelling | doaj.art-49b49f49368449519694ba53e10ff7b92022-12-21T20:01:54ZfasQom University of Medical SciencesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum1735-77992008-13752019-06-011341121Association of Dietary Quality Indices and Glioma: A Case-Control StudySeyed Mohammad Mousavi0Omid Sadeghi1Mahdi Shayanfar2Ahmad Esmaillzadeh3 Department of Community Nutrition, School of Nutritional Sciences and Dietetics Tehran University of Medical Sciences Department of Clinical Nutrition and Dietetics, National Nutrition and Food Technology Research Institute Department of Community Nutrition, School of Nutritional Sciences and Dietetics Background and Objectives: Glioma is the most common primary brain tumor, which mostly occurs in adults and is associated with high mortality. The purpose of this study was to investigate the association of food quality indices and glioma in Iranian adults. Methods: This case-control study was performed on 128 patients with glioma and 256 healthy individuals (matched for age and gender) in hospitals affiliated to Shahid Beheshti University of Medical Sciences, Tehran, between 2009 and 2011. Dietary assessment was performed using a validated block-format 123-item semi-quantitative food frequency questionnaire. Dietary Indices (DDS, AHEI-2010) were developed based on standard methods. Data were analyzed by independent t-test, Chi-Square and ANOVA. Results: In this study, after controlling for potential confounders, a significant inverse association was found between DDS and risk of glioma (OR: 0.39, 95% CI: 0.17-0.89). This finding was also seen when further adjustment was made for BMI; so that participants in the highest quartile of DDS, were 59% less likely to have glioma compared to those in the lowest quartile (OR: 0.41, 95% CI: 0.18 - 0.93). In addition, a significant inverse association was found between adherence to AHEI and glioma; such that in the fully adjusted model, the participants in the fourth quartile of AHEI had 62% lower risk of glioma compared to those in the the first quartile (OR: 0.38, 95% CI: 0.17-0.84). Conclusion: The results of this study showed that following a high-diversity healthy diet is associated with reduction in the risk of glioma.http://journal.muq.ac.ir/article-1-2260-en.htmlgliomaneoplasmschronic diseasedietary acid loadcase-control study |
| spellingShingle | Seyed Mohammad Mousavi Omid Sadeghi Mahdi Shayanfar Ahmad Esmaillzadeh Association of Dietary Quality Indices and Glioma: A Case-Control Study Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum glioma neoplasms chronic disease dietary acid load case-control study |
| title | Association of Dietary Quality Indices and Glioma: A Case-Control Study |
| title_full | Association of Dietary Quality Indices and Glioma: A Case-Control Study |
| title_fullStr | Association of Dietary Quality Indices and Glioma: A Case-Control Study |
| title_full_unstemmed | Association of Dietary Quality Indices and Glioma: A Case-Control Study |
| title_short | Association of Dietary Quality Indices and Glioma: A Case-Control Study |
| title_sort | association of dietary quality indices and glioma a case control study |
| topic | glioma neoplasms chronic disease dietary acid load case-control study |
| url | http://journal.muq.ac.ir/article-1-2260-en.html |
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